中西医结合治疗多发性斑秃疗效及远期复发情况观察

发布时间：2018-04-23 22:30

本文选题：中药汤剂治疗 + 斑秃　；参考：《中华中医药学刊》2017年04期

【摘要】：目的:观察中西医结合治疗多发性斑秃疗效及远期复发情况。方法:将就诊于医院脱发专病门诊的80例多发性斑秃患者,随机分为中西医结合组和西药组,每组各40例。所有患者常规使用基础性药物治疗:外用5%米诺地尔酊和0.05%丙酸氟替卡松乳膏。西药组予复方甘草酸苷片口服,中西医结合组口服止脱生发汤,连续治疗3个月后,判定临床疗效并进行统计学分析。结果:观察中西医结合组和西药组治疗后的临床疗效,中西医结合组的显效率为75.0%,总有效率为95.0%,西药组的显效率为27.5%,总有效率为77.5%,差异有统计学意义(P0.05)。中西医结合组进展期和静止期的显效率分别为76.2%,73.7%,西药组进展期和静止期的显效率分别为18.2%,38.9%,进行统计学比较,差异均有统计学意义(P0.05)。对两组中的痊愈患者随访1年,中西医结合组和西药组的复发率分别为17.6%和80%,两组比较,有统计学差异(P0.05)。结论:所采用中西医结合治疗多发性斑秃的方法较单纯使用西药的方法可以提高临床疗效,并可以降低远期复发率。在连续治疗的3个月期间,中西医结合组的患者出现药物相关的不良反应少且轻微。本研究采用的中西医结合治疗多发性斑秃的方法值得临床推广使用。
[Abstract]:Objective: to observe the curative effect and long-term recurrence of multiple alopecia areata treated with integrated traditional Chinese and western medicine. Methods: 80 patients with multiple alopecia areata were randomly divided into integrated Chinese and western medicine group and western medicine group with 40 cases in each group. All patients were treated with basic drugs: 5% minoxidil tincture and 0.05% fluticasone propionate cream. The western medicine group was treated with compound glycyrrhizin tablets and the integrated traditional Chinese and western medicine group with Zhitoushengfa decoction. After 3 months of continuous treatment, the clinical efficacy was evaluated and statistically analyzed. Results: to observe the clinical curative effect after treatment in the combination of traditional Chinese and western medicine group and western medicine group, the effective rate was 75.00.The total effective rate was 95.0, the effective rate was 27.5g and the total effective rate was 77.5in the western medicine group, the difference was statistically significant (P 0.05). The effective rates of the advanced stage and the stationary stage of the integrated traditional Chinese and western medicine group were 76.2and 73.7, respectively, and those of the western medicine group were 18.2and 38.9, respectively. The difference was statistically significant (P 0.05). The recurrence rates of the two groups were 17.6% and 80%, respectively. There was significant difference between the two groups (P 0.05). Conclusion: the treatment of multiple alopecia areata with combination of traditional Chinese and western medicine can improve the clinical efficacy and reduce the long term recurrence rate. During the 3 months of continuous treatment, patients in the integrated Chinese and western medicine group had less and mild adverse drug-related reactions. The treatment of multiple alopecia areata with integrated traditional Chinese and western medicine is worth popularizing.
【作者单位】：杭州市第三人民医院皮肤科;
【分类号】：R758.71

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