中西医结合治疗对类风湿性关节炎并发肺间质纤维化患者肺功能和血气指标的影响

发布时间：2018-05-13 12:24

本文选题：类风湿性关节炎并发肺间质纤维化 + 中西医结合　；参考：《辽宁中医杂志》2017年11期

【摘要】：目的:探讨中西医结合治疗对类风湿性关节炎(RA)并发肺间质纤维化患者肺功能和血气指标的影响。方法:选取RA并发肺间质纤维化患者60例,并依据治疗方式不同分为治疗组(n=30)和对照组(n=30),对照组采用强的松治疗;治疗组在对照组的基础上加用活血化瘀、补益脾肾方治疗,1周为1个疗程,两组均连续治疗4个疗程。统计并比较两组患者临床疗效;检测并比较两组患者治疗前后肺功能、血气指标及ESR、CRP、RF水平变化。结果:治疗组总有效率为93.33%,显著高于对照组的73.33%(P0.05);治疗后两组FEV1、FVC、FEV1/FVC均较治疗前显著上升(P0.05或P0.01),且治疗组显著高于对照组(P0.05或P0.01);治疗后两组Pa O2和Sa O2水平均较治疗前显著上升,Pa CO2水平较治疗前显著下降(P0.01),且组间差异显著(P0.05或P0.01);治疗后两组RF、ESR和CRP均显著低于治疗前(P0.05或P0.01),且治疗组显著低于对照组(P0.05或P0.01)。结论:中西医结合治疗RA并发肺间质纤维化疗效确切,可有效缓解临床体征,并能改善患者肺功能和血气指标水平,降低ESR、CRP、RF水平。
[Abstract]:Objective: to investigate the effects of integrated traditional Chinese and western medicine on pulmonary function and blood gas index in patients with pulmonary interstitial fibrosis complicated with rheumatoid arthritis (RA). Methods: sixty patients with RA complicated with pulmonary interstitial fibrosis were divided into two groups according to different treatment methods: the treatment group was divided into two groups: the treatment group and the control group, the control group was treated with prednisone, the treatment group was treated with prednisone, and the treatment group was treated with promoting blood circulation and removing blood stasis. Tonifying spleen and kidney prescription for 1 week was a course of treatment, both groups were treated continuously for 4 courses. The changes of lung function, blood gas index and the level of CRP RF before and after treatment were detected and compared between the two groups. Results: the total effective rate of the treatment group was 93.33, which was significantly higher than that of the control group (73.33), and the FEV _ 1 / FV _ 1 / FVC of the two groups were significantly higher than that of the control group (P 0.05 or P 0.01) after treatment, and the levels of Pao _ 2 and sa _ 2 in the treatment group were significantly higher than those in the control group (P 0.05 or P 0.01) after the treatment, and the FEV _ 1 / FV _ (1) / FV _ (1) / FVC of the two groups were significantly higher than those before the treatment. After treatment, the levels of CO2 and CRP in the two groups were significantly lower than those in the control group (P 0.05 or P 0.01), and that in the treatment group was significantly lower than that in the control group (P 0.05 or P 0.01). Conclusion: integrated traditional Chinese and western medicine is effective in treating RA complicated with pulmonary interstitial fibrosis, which can effectively relieve clinical signs, improve the pulmonary function and blood gas index, and decrease the level of CRP RF in patients with RA.
【作者单位】：青岛海慈医疗集团全科医学科;青岛海慈医疗集团肝胆内科;青岛海慈医疗集团风湿免疫科;
【分类号】：R563;R593.22

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