中西医结合治疗对冠心病患者生存质量改善的随机对照研究

发布时间：2018-05-14 11:54

本文选题：冠心病患者 + 随机对照研究　；参考：《辽宁中医杂志》2010年01期

【摘要】：目的:编制一套有中华文化内涵的冠心病(CAD)生存质量量表,用以评价中西医结合治疗CAD的临床疗效。方法:采用随机、对照、单盲方法,将129例CAD患者分为中西医结合治疗组(简称治疗组)和常规治疗组(简称对照组),其中治疗组72例和对照组57例。对照组予常规西药如抗血小板药物、硝酸酯类药物、β-受体阻滞剂、钙离子拮抗剂、血管紧张素转化酶抑制剂(ACEI)等;治疗组在常规西药基础上辨证施治,加用中药汤剂和中成药。本研究主要观察治疗前后生存质量的改善情况。结果:(1)治疗后与治疗前相比,治疗组和对照组生存质量情况均有一定程度的改善,差异具有统计学意义(P0.05),但治疗组改善更明显;(2)治疗前,治疗组和对照组各维度计分差别无统计学意义(P0.05),治疗后,治疗组患者在"临床主要症状"、"疾病伴随情况"、"疾病认识程度"方面与对照组比较有提高,差异具有统计学意义(P0.05),而在其余"躯体活动受限程度"、"疾病发作情况"、"疾病诱发因素"、"治疗满意程度"四个方面两组差异无统计学意义(P0.05)。结论:(1)中西医结合治疗能显著改善冠心病患者的生存质量。(2)中西医结合治疗后的患者,生存质量随时间的推移改善越明显。
[Abstract]:Objective: to prepare a set of Chinese cultural connotations of coronary heart disease (CAD) quality of life scale to evaluate the clinical effect of the combination of traditional Chinese and Western medicine in the treatment of CAD. Methods: 129 cases of CAD patients were divided into two groups: the combination of traditional Chinese and Western Medicine (treatment group) and the conventional treatment group (abbreviated as the control group), of which 72 cases and the control group were treated as the control group. Group 57 cases. The control group was given conventional western medicine such as antiplatelet drugs, nitrates, beta blockers, calcium antagonists and angiotensin converting enzyme inhibitor (ACEI). The treatment group was treated on the basis of conventional western medicine, combined with Chinese herbal decoction and Chinese patent medicine. The improvement of the quality of life before and after treatment was observed. (1) after treatment, compared with before treatment, the quality of life of the treatment group and the control group had some improvement, the difference was statistically significant (P0.05), but the improvement of the treatment group was more obvious; (2) before the treatment, the difference between the treatment group and the control group was not statistically significant (P0.05). After the treatment, the treatment group was in "clinical major symptoms", "disease", "disease". The degree of disease awareness was higher than that of the control group. The difference was statistically significant (P0.05), but there was no significant difference between the two groups (P0.05) in the four aspects of the degree of physical activity limitation, disease attack, disease inducing factors and treatment satisfaction (P0.05). (1) the combination of Chinese and Western medicine could be significantly modified. The quality of life of patients with coronary heart disease is good. (2) the quality of life of patients with integrated traditional Chinese and Western medicine improved significantly over time.

【作者单位】：天津中医药大学;天津中医药大学第一附属医院;
【基金】：天津市科技攻关计划重大科技项目(05YFGDSF02200)
【分类号】：R541.4

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