中西医结合对鼻内镜手术后鼻黏膜的影响

发布时间：2018-05-18 04:12

本文选题：鼻内镜术 + 鼻窦术　；参考：《南方医科大学学报》2010年03期

【摘要】：目的鼻内镜术后应用自制中药液加西药液冲洗鼻腔,观察对鼻腔黏膜的影响。方法鼻内镜手术患者100例,随机分为两组:对照组50例患者用生理盐水250ml加庆大霉素(80000U)和地塞米松(5mg),于术后第2天取出鼻腔油纱条开始鼻腔冲洗,前两个月2次/d,第3个月1次/d。实验组50例患者在对照组基础上给予自制中药洗液250ml冲洗。术中、术后3个月用鼻内镜取患者鼻道窦口周围黏膜,采用免疫组化技术观察术后黏膜iNOS表达情况。结果实验组疗效明显优于对照组,术中实验组及对照组iNOS无统计学差异,术后3个月实验组阴性率明显高于对照组(P0.05)。结论术后用中西药液结合冲洗鼻腔可以通过调节鼻腔黏膜的iNOS修复鼻息肉术后黏膜,提高鼻内镜手术的疗效。
[Abstract]:Objective to observe the effect of Chinese traditional medicine plus western medicine on nasal cavity after nasal endoscopy. Methods 100 patients undergoing endoscopic sinus surgery were randomly divided into two groups: the control group (50 cases) was treated with saline 250ml plus gentamicin 80000U) and dexamethasone (5 mg / g), the nasal cavity oil gauze was taken out on the second day after operation and the nasal cavity was washed. Two times in the first two months, one in the third month. On the basis of the control group, 50 patients in the experimental group were washed with 250ml. The mucous membrane around the sinus orifice of the patients was removed by nasal endoscope 3 months after operation. The expression of iNOS was observed by immunohistochemical technique. Results the efficacy of the experimental group was better than that of the control group. There was no significant difference in iNOS between the experimental group and the control group during the operation. The negative rate of the experimental group was significantly higher than that of the control group 3 months after operation. Conclusion after operation, the nasal cavity can be repaired by regulating the nasal mucous membrane with iNOS, and the curative effect of nasal endoscopic surgery can be improved by using traditional Chinese medicine and western medicine in combination with rinsing nasal cavity.
【作者单位】：上海市徐汇区中心医院耳鼻咽喉科;
【分类号】：R765.41

【共引文献】