加用通痹止痛汤内服的中西医结合治疗AGA64例临床观察

发布时间：2018-06-05 04:22

本文选题：急性痛风性关节炎 + 通痹止痛汤　；参考：《重庆医学》2016年05期

【摘要】：目的观察通痹止痛汤联合秋水仙碱加塞来昔布的中西医结合方案治疗急性痛风性关节炎(AGA)的临床疗效。方法将125例AGA患者分为对照组(n=61)和观察组(n=64)。对照组采用秋水仙碱片加塞来昔布胶囊治疗,观察组在对照组基础上加用通痹止痛汤内服,疗程均为14d。采用视觉模拟评分(VAS)法进行评价,记录两组患者疼痛缓解时间,检测治疗前、后血尿酸(UA)、红细胞沉降率(ESR)、C-反应蛋白(CRP)、白细胞介素1(IL-1)和肿瘤坏死因子α(TNF-α)水平。结果治疗后观察组关节疼痛、压痛、红肿、活动障碍评分低于对照组(P0.01),医生整体评价和患者整体评价高于对照组(P0.05),疼痛缓解时间短于对照组(P0.05);治疗后观察组ESR、UA、CRP、IL-1和TNF-α低于对照组(P0.01)。结论中西医结合治疗方案在减轻AGA疼痛,改善症状、减轻炎症反应、降低UA等方面均具有更明显的优势,能更有效、更快控制AGA的发作。
[Abstract]:Objective to observe the clinical effect of Tongbi Zhitong decoction combined with colchicine plus Salichib in the treatment of acute gouty arthritis (AGA). Methods 125 patients with AGA were divided into control group (n = 61) and observation group (n = 64). The control group was treated with colchicine tablet plus Salichib capsule, the observation group was treated with Tongbi Zhitong decoction on the basis of the control group, the course of treatment was 14 days. Visual analogue scale (VAS-VAS) was used to evaluate the pain relief time of the two groups. Before and after treatment, the levels of serum uric acid, erythrocyte sedimentation rate (ESR), C-reactive protein (CRP), interleukin-1 (IL-1) and tumor necrosis factor- 伪 (TNF- 伪) were measured. Results after treatment, the scores of pain, tenderness, swelling and dyskinesia in the observation group were lower than those in the control group (P 0.01), the overall evaluation of doctors and patients was higher than that in the control group (P 0.05), the time of pain relief was shorter than that in the control group, and the levels of IL-1 and TNF- 伪 in the observation group were lower than those in the control group (P 0.01). Conclusion the combination of traditional Chinese and western medicine has more advantages in alleviating pain, improving symptoms, alleviating inflammatory reaction and decreasing UA in AGA. It is more effective and can control the attack of AGA more quickly.
【作者单位】：青海大学附属医院血液风湿科;
【分类号】：R589.7

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