阴道微生态与中西医结合治疗阴道炎的临床疗效观察

发布时间：2018-06-20 02:55

本文选题：阴道微生态 + 阴道炎　；参考：《云南中医学院》2017年硕士论文

【摘要】：目的:阴道炎(Vaginitis)是最多见的女性生殖道感染性疾病,有较高的复发性。本文通过探讨中西医结合治疗妇科常见阴道炎的疗效,并对相关微生态进行评估,通过临床试验,为治疗阴道炎寻找一种最佳的治疗方法,为临床用药提供客观实验依据。方法:选取我院门诊及住院诊治的阴道炎患者600例,其中外阴阴道假丝酵母菌病300例,细菌性阴道病300例,每种疾病根据治疗方法的不同分为中医治疗组、西医治疗组以及中西医结合治疗组,每组患者各100例。所选患者均进行7天一疗程的治疗,在治疗前后对阴道分泌物染色标本结果评价---Nugent评分,并对阴道PH值、过氧化氢、白细胞酯酶、唾液酸苷酶的变化分析,进而对其进行微生态分析,采用统计学软件SPSS19.0进行分析。结果:细菌性阴道病年龄分布结果可见22-31岁之间的患者最多占42%,其次为32-41岁之间占28%,再次为小于22岁的占24%。外阴阴道假丝酵母菌病患者300例,其年龄分布结构可见22-31岁之间的患者最多占40%,其次为32-41岁之间占32%,再次为小于22岁的患者占23%。细菌性阴道病患者300例,中医证型分布结果显示湿热下注证患者最多占44%,脾虚湿盛证占40%,肾阳虚证占12%,温毒蕴结证占4%。外阴阴道假丝酵母菌性阴道炎患者300例,中医证型分布结果显示患者湿热下注证最多占46%,脾虚湿盛证占38%,肾阳虚证占11%,温毒蕴结证占5%;治疗后,细菌性阴道病患者、外阴阴道假丝酵母菌病患者的中西医治疗有效率明显高于单纯中医、西医治疗组,差异有统计学意义(p0.05):而单纯中医治疗与西医治疗组间比较有效率差异不显著,无统计学意义(p0.05),PH值、过氧化氢、白细胞酯酶以及唾液酸苷酶治疗前后相比较(p0.05),具有统计学意义。结论:三组治疗方法治疗细菌性阴道病、外阴阴道假丝酵母菌病具有一定的疗效,其中西医联合中药熏洗方治疗效果最优。
[Abstract]:Objective: Vaginitis is the most common infectious disease in female genital tract. This article discusses the curative effect of the treatment of gynecological common vaginitis with the combination of traditional Chinese and western medicine, and evaluates the related microecology. Through the clinical trial, we seek a kind of best treatment method for treating vaginitis, and provide the objective experimental basis for the clinical use of drugs. Methods: a total of 600 patients with vaginitis were selected, including 300 cases of vulvovaginal candidiasis and 300 cases of bacterial vaginosis. Western medicine treatment group and integrated Chinese and western medicine treatment group, each group of 100 patients. All the patients were treated for 7 days. The results of vaginal discharge staining were evaluated by -Nugent score before and after treatment, and the changes of PH value, hydrogen peroxide, leucocyte esterase and sialidase were analyzed. Then the microecological analysis was carried out and the statistical software SPSS 19.0 was used to analyze it. Results: the age distribution of bacterial vaginosis showed that 42 22 cases were aged 22 to 31 years old, 28 cases were between 32 and 41 years old, and 24 cases were younger than 22 years old. There were 300 cases of vulvovaginal candidiasis. The age distribution structure showed that 40 cases were between 22 and 31 years old, 32 cases were between 32 and 41 years old, and 23 cases were younger than 22 years old. There were 300 patients with bacterial vaginosis. The distribution of TCM syndromes showed that the most 44 cases were damp-heat betting syndrome, 40 cases were spleen deficiency dampness syndrome, 12 cases were kidney yang deficiency syndrome, and 4 cases were warm toxin accumulation syndrome. In 300 cases of vulvovaginal candida vaginitis, the distribution of TCM syndromes showed that the maximum number of patients with dampness and heat betting syndrome was 46, spleen deficiency dampness syndrome was 38, kidney yang deficiency syndrome was 11 and warm toxin accumulation syndrome was 50.After treatment, bacterial vaginosis patients, The effective rate of traditional Chinese medicine and western medicine in vulvovaginal Candida cerevitis patients was significantly higher than that in traditional Chinese medicine group and western medicine treatment group, the difference was statistically significant (p 0.05). However, there was no significant difference in effective rate between traditional Chinese medicine treatment group and western medicine treatment group. There was no significant difference in PH value between before and after treatment with hydrogen peroxide, leucocyte esterase and sialidase. Conclusion: three groups of treatment methods for bacterial vaginosis vulvovaginal candidiasis has a certain curative effect its traditional Chinese and Western medicine combined with Chinese medicine fumigation and washing prescription is the best.
【学位授予单位】：云南中医学院
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R711.31

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