中西医结合心竭宁方治疗冠心病慢性心衰临床观察

发布时间：2018-07-06 09:06

本文选题：心竭宁方 + 慢性充血性心力衰竭　；参考：《辽宁中医杂志》2007年09期

【摘要】：目的:探讨中西医结合心竭宁方治疗冠心病慢性心衰临床疗效。方法:根据纳入排除标准,选取冠心病慢性心衰患者60例,按心功能水平分层,随机分为治疗组和对照组两组,以安全指标(血尿常规和肝肾功能)和疗效指标(包括中西医疗效、中医证候学积分、心功能、明尼苏达生活质量评分6min步行试验)为观察指标,观察周期为2周。结果:中西医结合心竭宁治疗组中西医总疗效均优于单纯西药对照组,中医心衰主症积分观察显示心竭宁治疗组在心悸、气短而喘等症状改善方面亦有优势,但咳嗽改善不明显。心脏收缩功能指标(FS%、SV和EF%)组间及组内均有统计学差异(P0.05)。但明尼苏达生活质量评分及6min步行试验组间差异无统计学意义(P0.05)。结论:中西医结合心竭宁方治疗冠心病气虚血瘀、水湿内停型慢性心衰有一定的综合疗效优势,尤其在改善心悸气短等症状方面,但生活质量评分和六分钟步行试验尚未显示统计学差异优势。
[Abstract]:Objective: to investigate the clinical effect of Xindaoning prescription combined with traditional Chinese medicine and western medicine on chronic heart failure of coronary heart disease. Methods: according to the exclusion criteria, 60 patients with chronic heart failure of coronary heart disease were randomly divided into two groups: treatment group and control group according to the level of cardiac function. The safety index (routine blood and urine routine and liver and kidney function) and curative effect index (including TCM curative effect, TCM syndromes score, cardiac function, Minnesota quality of life score 6min walking test) were used as observation indexes. The observation period was 2 weeks. Results: the total curative effect of traditional Chinese and western medicine combined with Xinzaoning Ning group was better than that of western medicine control group. The integral observation of main symptoms of heart failure in traditional Chinese medicine showed that the treatment group also had advantages in the improvement of palpitation, shortness of breath and asthma, etc. But the cough did not improve significantly. There were significant differences in cardiac systolic function (FSSV and EF%) between groups and within groups (P0.05). However, there was no significant difference between Minnesota quality of life score and 6min walking test group (P0.05). Conclusion: the combination of traditional Chinese and western medicine in treating chronic heart failure with deficiency of qi and blood stasis and internal arrest of water and dampness, especially in improving the symptoms of heart palpitation and shortness of breath, is effective in treating coronary heart disease with Qi deficiency and blood stasis. However, the quality of life score and the six-minute walking test did not show statistically significant differences.
【作者单位】：北京中医药大学东方医院急诊科中国中医科学院望京医院心内科北京中医药大学东方医院心内科北京中医药大学东方医院急诊科北京市中西医结合王府医院
【分类号】：R541.4;R541.6

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