中西医结合治疗卵巢早衰58例疗效观察

发布时间：2018-07-21 12:50

【摘要】：目的观察中西医结合治疗卵巢早衰的临床疗效。方法将152例卵巢早衰患者随机分为3组。中西医结合治疗组(中西医结合组)58例,采用抗卵衰冲剂与人工周期方案治疗,人工周期对照组(人工周期组)58例,仅用西药人工周期方案治疗,抗卵衰冲剂对照组(中药组)36例,仅采用抗卵衰冲剂治疗,3组疗程均为3个月。结果3组疗效间差异有统计学意义(χ2=19.22,P0.01)。3组患者血促卵泡激素(FSH)、促黄体生长素(LH)、血清雌二醇(E2)治疗前差异均无统计学意义(P0.05),3组患者治疗后血促卵泡激素、血清雌二醇间差异均有统计学意义(P0.05);但3组治疗后血清LH间差异无统计学意义(P0.05)。治疗后3组患者子宫内膜厚度间差异有统计学意义(F=5.14,P0.01)。3组患者均无明显不良反应。结论抗卵衰冲剂联合人工周期方案治疗卵巢早衰疗效确切、起效快,但其作用机制及其远期疗效有待进一步研究证实。
[Abstract]:Objective to observe the clinical effect of combination of traditional Chinese and western medicine on premature ovarian failure. Methods 152 patients with premature ovarian failure were randomly divided into 3 groups. 58 cases were treated with anti-ovalbule granule and artificial cycle regimen, and 58 cases with artificial cycle control group were treated with western medicine artificial cycle regimen only. There were 36 cases in the control group treated with Kangyaoshuai granule only for 3 months. Results there was no significant difference in serum follicle stimulating hormone (FSH), luteinizing hormone (LH) and serum estradiol (E _ 2) between the three groups (蠂 ~ (2 +) (19.22) P _ (0.01) before and after treatment (P0.05), and there was no significant difference in serum follicle stimulating hormone (FSH), luteinizing hormone (LH) and serum estradiol (E _ 2) before treatment (P0.05). The differences of serum estradiol were statistically significant (P0.05), but there was no significant difference in serum LH after treatment (P0.05). After treatment, there was no significant difference in endometrial thickness between the three groups (FF5. 14, P0.01). Conclusion the effect of Kangoshuai granule combined with artificial cycle regimen on premature ovarian failure is definite and effective, but its mechanism and long term effect need to be further studied and confirmed.
【作者单位】：河北省中医院河北省河间市医院河北省中医院河北省中医院河北省中医院河北省中医院河北省中医院
【基金】：河北省科技厅2006年科技攻关项目(062761780)
【分类号】：R711.7

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