癌因性疲劳与下丘脑-垂体-肾上腺轴关系研究进展

发布时间：2018-01-27 09:35

本文关键词： 癌因性疲劳下丘脑-垂体-肾上腺轴皮质醇综述　出处：《中国康复理论与实践》2017年04期 　论文类型：期刊论文

【摘要】：癌因性疲劳患者清晨血清皮质醇浓度较非疲劳患者低,其昼夜节律变化幅度较小,面对压力时皮质醇反应较迟钝。其机制可能与下丘脑-垂体-肾上腺轴失调导致炎症反应相关,也有证据支持皮质类固醇激素短期内使用能够改善癌因性疲劳。本文就近年来癌因性疲劳与下丘脑-垂体-肾上腺轴关系的研究进展进行综述。
[Abstract]:The serum cortisol concentration in patients with carcinogenic fatigue was lower than that in non-fatigue patients, and the circadian rhythm was smaller. Cortisol is less responsive to stress. The mechanism may be associated with the hypothalamus-pituitary-adrenal axis imbalance leading to inflammation. There is also evidence that corticosteroids can improve carcinogenic fatigue in the short term. This article reviews the recent advances in the relationship between carcinogenic fatigue and hypothalamus-pituitary-adrenal axis (hypothalamus-pituitary-adrenal axis).
【作者单位】：上海中医药大学研究生院;上海长海医院康复医学科;
【基金】：上海市中医药发展三年行动计划项目(No.ZY3-CCCX-3-7002)
【分类号】：R730.5
【正文快照】： [本文著录格式]苏羚子,李柏.癌因性疲劳与下丘脑-垂体-肾上腺轴关系研究进展[J].中国康复理论与实践,2017,23(4):406-409.CITED AS:Su LZ,Li B.Relationship between cancer-related fatigue and hypothalamic-pituitary-adrenal axis(review)[J].ZhongguoKangfu Lilun Yu Shi

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