福建省局部地区消化系统主要癌种空间自相关分析

发布时间：2018-01-29 14:30

  本文关键词： 消化系统肿瘤 空间自相关 空间流行病学　出处：《中国公共卫生》2017年04期 　论文类型：期刊论文

【摘要】：目的探索福建省部分肿瘤登记地区以乡镇为尺度的食管癌、胃癌、结直肠癌和肝癌等消化系统主要恶性肿瘤空间分布特征和聚集性。方法于2007—2012年以福建省长乐市、涵江区和福清市3个肿瘤登记处作为研究现场,收集4种消化系统主要恶性肿瘤分乡镇发病率,应用Arc GIS 10.3软件进行全局和局部Moran's I、G统计量自相关分析。结果食管癌、胃癌、结直肠癌和肝癌全局Moran's I分别为0.734 011、0.932 897、0.633 696和0.644 418(均P0.001);食管癌、胃癌、结直肠癌全局G统计量分别为0.000 024、0.000 020和0.000 017(均P0.001)。局部Moran's I自相关显示,食管癌有11个H-H(高-高值)区域;胃癌有8个H-H区域、7个L-L(低-低值)区域;结直肠癌有8个H-H区域、1个H-L(高-低值)区域、6个L-L区域;肝癌有11个H-H区域、1个L-H(低-高值)区域、8个L-L区域。局部G自相关结果显示,食管癌有3个冷点和1个热点;胃癌有4个冷点和2个热点;结直肠癌有6个冷点和1个热点;肝癌有1个冷点和2个热点。结论消化系统主要恶性肿瘤在乡镇级别空间上呈现非随机分布,4个癌种均有其独特的热点、冷点以及发病率高低交错的聚集区域。
[Abstract]:Objective to explore esophageal and gastric cancer with township scale in some tumor registration areas in Fujian Province. The spatial distribution and aggregation of major malignant tumors in digestive system, such as colorectal cancer and liver cancer, were studied in Changle City, Fujian Province from 2007 to 2012. Three tumor registries in Hanjiang District and Fuqing City were used as research sites to collect the incidence of 4 major digestive system malignant tumors in villages and towns. The global and local Moran's Ig statistics were analyzed by Arc GIS 10.3 software. Results esophageal and gastric cancer. The global Moran's I of colorectal cancer and liver cancer were 0.734 011 ~ 0.932 897 ~ 0.633 696 and 0.644 418 respectively (P 0.001). The global G statistics of esophageal cancer, gastric cancer and colorectal cancer were 0.000024 respectively. 0. 000 020 and 0. 000 017 (P 0. 001). Local Moran's I autocorrelation showed that there were 11 H-H (high to high) regions in esophageal carcinoma. There were 8 H-H regions and 7 L-L (low-low value) regions in gastric cancer. There were 8 H-H regions, 1 H-L (high-low value) region and 6 L-L regions in colorectal cancer. There were 11 H-H regions, 1 L-H region and 8 L-L regions in HCC. Local G autocorrelation showed that esophageal carcinoma had three cold points and one hot spot. Gastric cancer had 4 cold spots and 2 hot spots. There were 6 cold spots and 1 hot spot in colorectal cancer. Conclusion the main malignant tumors of digestive system have a non-random distribution in township level, and all of them have their own unique hot spots. Cold spots and areas where the incidence rate is interlaced.
【作者单位】： 福建省肿瘤医院流行病室;福建医科大学公共卫生学院流行病与卫生统计系福建省环境因素与肿瘤重点实验室;福建省疾病预防控制中心;
【基金】：国家临床重点专科建设项目 福州市科技计划项目(2015-S-163)
【分类号】：R735
【正文快照】： 2012年全国肿瘤登记地区恶性肿瘤发病前10位有5种属于消化系统,胃癌、肝癌、结直肠癌和食管癌位居第2至第5位、仅次于肺癌;死亡前10位亦有5种属于消化系统,肝癌、胃癌、食管癌和结直肠癌位居第2至第5位、亦仅次于肺癌[1]。因此胃癌、肝癌、结直肠癌和食管癌目前是消化系统主要，

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