结直肠癌原发灶与肝转移灶的扩散成像比较

发布时间：2018-02-28 12:46

本文关键词： 结直肠癌扩散加权成像表观扩散系数肝转移瘤　出处：《临床放射学杂志》2017年02期 　论文类型：期刊论文

【摘要】：目的探讨结直肠癌原发灶与其肝转移灶之间在常规磁共振序列、扩散加权成像(DWI)及表观扩散系数(ADC)上的不同。方法对经病理或临床证实的85例结直肠癌患者及23例结直肠癌肝转移患者的磁共振表现进行回顾性分析,并以病灶T1WI-r SI、T2WI-r SI、DWI-r SI平均信号强度、ADC值作为评价标准。统计学方法采用两独立样本t检验、Mann-Whitney秩和检验及受试者工作特征(ROC)曲线图。结果结直肠癌原发灶与肝转移灶在T1WIr SI、T2WI-r SI、DWI-r SI平均信号强度及ADC之间具有显著差异(Z=-7.333,P0.05;t=6.112,P0.05;t=-3.892,P0.05;t=7.518,P0.05)。在结直肠癌肝转移灶的诊断中DWI-r SI与常规序列相对信号强度下的曲线面积(AUC)分别为0.940、0.786;在结直肠癌原发灶的诊断中DWI-r SI与常规序列相对信号强度的AUC分别为0.843、0.847。结论结直肠癌原发灶与肝转移灶之间在不同MRI序列存在信号差异,说明两者之间在其生物学特性上存在差异。DWI序列在对结直肠癌肝转移灶的诊断准确性高于常规序列,在原发灶的诊断准确性上相近。
[Abstract]:Objective to study the conventional magnetic resonance imaging (MRI) sequence between primary colorectal cancer and its hepatic metastases. Diffusion-weighted imaging (DWI) and apparent diffusion coefficient (ADCC). Methods the MRI findings of 85 patients with colorectal cancer and 23 patients with hepatic metastasis were retrospectively analyzed. The mean signal intensity and ADC value of T1WI-r SI DWI-r SI DWI-r SI were used as the evaluation standard. The Mann-Whitney rank sum test and the ROC curve of subjects were used in two independent sample t tests. Results the primary focus and hepatic metastasis of colorectal cancer were studied. There were significant differences in the mean signal intensity and ADC between T1WIr SIT2WI-r SIN DWI-r SI and ADC. The curve area of DWI-r SI and conventional sequence was 0.9400.786in the diagnosis of liver metastases of colorectal cancer, and in the diagnosis of colorectal cancer, the mean signal intensity of DWI-r SI was 0.9400.786, and the mean signal intensity of DWI-r SI was 0.9400.786.The mean signal intensity of DWI-r SI was 0.9400.786in the diagnosis of liver metastases of colorectal cancer, and the mean signal intensity of DWI-r was 0.9400.786in the diagnosis of colorectal cancer. The relative signal intensities of DWI-r SI and conventional sequences were 0.843 卤0.8477.Conclusion there are signal differences in different MRI sequences between primary and hepatic metastases of colorectal cancer. The results showed that the diagnostic accuracy of DWI sequence was higher than that of routine sequence in the diagnosis of liver metastases of colorectal cancer, and the diagnostic accuracy of primary tumor was similar.
【作者单位】：潍坊医学院;潍坊医学院附属医院影像中心;
【基金】：山东省医药卫生科技发展计划项目(编号:2013WS0276)
【分类号】：R445.2;R735.34

【相似文献】