乳腺癌患者术后感染及危险因素探讨

发布时间：2018-03-18 06:09

本文选题：乳腺癌　切入点：治疗　出处：《中华医院感染学杂志》2017年19期 　论文类型：期刊论文

【摘要】：目的探究乳腺癌患者在手术治疗后的临床感染情况及危险因素。方法回顾医院2013年6月-2016年6月期间收治的1080例乳腺癌手术治疗患者治疗情况,分析患者在术后的临床感染情况,病原菌的分布及发生感染的危险因素进行分析。结果 1080例患者中,出现感染的患者为37例,感染率3.43%,37例患者送检标本中共分离出病原菌49株,其中革兰阳性菌18株占36.73%,革兰阴性菌为23株占46.94%,真菌为8株占16.33%,37例感染患者以呼吸道感染为主,对革兰阳性菌进行耐药实验显示,金黄色葡萄球菌以及溶血葡萄球菌对万古霉素的耐药性最低,均为0,革兰阳性菌对万古霉素的耐药性较低,对革兰阴性菌进行耐药实验显示,铜绿假单胞菌对头孢他啶及美罗培南耐药率最低,为0,鲍氏不动杆菌对氨苄西林及美罗培南耐药率最低为0,大肠埃希菌对氨苄西林、舒巴坦、环丙沙星及美罗培南耐药率最低为0,肺炎克雷伯菌对美罗培南耐药率最低,为0,患者年龄、住院时间、是否联合放化疗等因素均是患者感染的危险因素(P0.05)。结论乳腺癌患者术后感染主要以呼吸道感染为主,并且多数的病原菌均存在各种程度的耐药性,在对患者治疗的过程中应远离可能造成患者感染的各种危险因素。
[Abstract]:Objective to investigate the clinical infection and risk factors of breast cancer patients after surgical treatment. The clinical infection, the distribution of pathogenic bacteria and the risk factors of infection were analyzed. Results among 1080 patients, 37 were infected. The infection rate was 3.430.A total of 49 pathogenic bacteria were isolated from 37 patients, of which 18 were Gram-positive bacteria (36.73cm), 23 Gram-negative bacteria (46.94), and 8 fungi (16.3333) were mainly respiratory tract infections. The drug resistance test of Gram-positive bacteria showed that Staphylococcus aureus and Staphylococcus haemolyticus had the lowest resistance to vancomycin, and Gram-positive bacteria were less resistant to vancomycin, and Gram-negative bacteria were resistant to vancomycin. Pseudomonas aeruginosa showed the lowest resistance to ceftazidime and meropenem (0), Acinetobacter baumannii to ampicillin and meropenem (0), Escherichia coli to ampicillin and sulbactam. The lowest resistance rate of ciprofloxacin and meropenem was 0, and the resistance rate of Klebsiella pneumoniae to meropenem was the lowest (0). Conclusion postoperative infection of breast cancer patients is mainly caused by respiratory tract infection, and most of the pathogens have various drug resistance. In the course of treatment of patients should be away from the risk factors that may lead to infection.
【作者单位】：新乡医学院第一附属医院普外科;
【基金】：河南省卫生厅科技攻关基金资助项目(201303104)
【分类号】：R737.9

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