经阴道超高速剪切波弹性成像对宫颈癌及癌前病变的诊断价值

发布时间：2018-03-21 04:37

  本文选题：宫颈癌　切入点：癌前病变　出处：《临床和实验医学杂志》2017年24期 　论文类型：期刊论文

【摘要】：目的探讨经阴道超高速剪切波弹性成像对宫颈癌及癌前病变的诊断作用。方法回顾性分析2014年5月至2017年5月期间收治的48例宫颈恶性病变患者的临床资料,比较宫颈癌组(n=18)、宫颈上皮内瘤变(CIN)组(n=30)和体检健康、宫颈无病变的对照组(n=53)的宫颈弹性成像硬度评分、平均弹性成像硬度评分诊断宫颈癌的敏感度和特异度、感兴趣区域弹性模量最大值和平均值、弹性模量最大值和平均值诊断宫颈癌及CIN的ROC曲线下面积。结果宫颈癌组的平均弹性成像硬度评分为(3.93±0.08)分,均分别高于对照组的(1.05±0.03)分、CIN的组(2.12±0.06)分,差异有显著性(P0.05)。以评分≥3分诊断为宫颈癌,其敏感度为94.44%,特异度为88.89%。宫颈癌组感兴趣区域弹性模量最大值及平均值最高,与CIN组、对照组比较差异有统计学意义(P0.05)。宫颈癌弹性模量最大值及平均值诊断宫颈癌的ROC曲线下面积分别为0.92、0.75(Z=3.541,P0.05)。结论经阴道超高速剪切波弹性成像技术可定量分析宫颈组织软硬度,有利于筛查早期宫颈癌,并可通过彩色编码筛查浸润程度,但对癌前病变的诊断价值并不明显。
[Abstract]:Objective to investigate the role of transvaginal ultra-high speed shear wave elastography in the diagnosis of cervical cancer and precancerous lesions. Methods the clinical data of 48 patients with cervical malignant lesions from May 2014 to May 2017 were retrospectively analyzed. The sensitivity and specificity of cervical elastography hardness score and mean elastography hardness score were compared between cervical carcinoma group (n = 18), cervical intraepithelial neoplasia group (n = 30) and healthy control group (n = 53). The area under the ROC curve of cervical cancer and CIN was diagnosed by the maximum and average elastic modulus of the region of interest. Results the average elastic imaging hardness score of cervical cancer group was 3.93 卤0.08. The difference was significant (P < 0.05). The sensitivity and specificity of diagnosis of cervical cancer with score 鈮，

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