食管癌术后局部复发危险因素以及预后分析

发布时间：2018-03-27 19:47

  本文选题：食管癌术后　切入点：局部复发　出处：《河北医科大学》2017年硕士论文

【摘要】：目的:通过收集食管癌术后局部复发患者的临床资料,从获得的各种数据进行统计学分析,找出局部复发的规律以及术后复发影响预后的危险因素。方法:收集河北医科大学第四医院2008-2015年在我院行食管癌根治术(术前经CT、MRI、超声、骨扫描等相关检查均未发现远处转移),术后发生局部复发、转移并且就诊于我院放射治疗科行放疗的病人共706例的临床资料。局部复发包括:锁骨上淋巴结转移、上纵膈淋巴结转移、中下纵膈淋巴结转移、吻合口复发或者食管原瘤床复发、腹腔淋巴结转移。术后淋巴结复发的诊断标准总结如下:1、经过穿刺得到病理学或细胞学上的诊断;2、影像学中的诊断:一般认为可见的淋巴结短径≥10mm可认为是区域淋巴结复发。吻合口复发诊断标准:食管镜下可见新生物及咬检病理证实或者CT以及PET-CT可见不规则软组织肿块以及异常高代谢区。采用软件spss21.0进行统计学分析,生存时间为从手术时间到死亡时间或最后一次随访时间,计数资料采用?2检验,生存分析采用Kaplan-Meier法,行Log-rank检验,多因素预后分析采用Cox模型,P
[Abstract]:Objective: to collect the clinical data of patients with local recurrence of esophageal cancer after operation, and to analyze the data obtained statistically. To find out the regularity of local recurrence and the risk factors of postoperative recurrence affecting prognosis. Methods: the fourth Hospital of Hebei Medical University performed radical resection of esophageal carcinoma in our hospital from 2008 to 2015. The clinical data of 706 patients who were treated with radiotherapy in radiotherapy department of our hospital were not found in bone scanning. The local recurrence included supraclavicular lymph node metastasis. Lymph node metastasis of upper mediastinum, lymph node metastasis of middle and lower mediastinum, recurrence of anastomotic stoma or recurrence of esophageal tumor bed, The diagnostic criteria for lymph node recurrence after operation are summarized as follows: 1. Pathological or cytological diagnosis is obtained by puncture. Diagnosis in imaging: the visible short diameter of lymph node 鈮，

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