中医五音疗法改善乳腺癌患者化疗应激状态的临床研究

发布时间：2018-03-29 06:12

本文选题：中医五音疗法　切入点：乳腺癌　出处：《南京中医药大学》2017年硕士论文

【摘要】：目的:本研究意在观察五音疗法对乳腺癌患者化疗期应激状态的影响。探索非药物疗法对乳腺癌患者化疗期应激状态的干预机制。方法:将乳腺癌患者化疗的40例符合纳入标准的患者分为两组:治疗组20例,在化疗及基础治疗的同时戴耳机听音乐,每日上、下午各一次,每次20min 2个疗程(21天为1个疗程);对照组20例,单纯化疗及基础治疗。上述两组在第一次化疗前及化疗第2、4及下一个化疗周期的前一天、化疗第2、4天评价疗效,比较两组患者化疗毒副作用、应激状态症状评分、生活质量评估、心理评分、白细胞计数、血小板计数、一氧化氮、超氧化物歧化酶、细胞免疫。结果:实验结束后,实验组和对照组有效病例均为20例。结果如下:实验采用应激状态观察表、一氧化氮(NO)和超氧化物歧化酶(SOD)的测定,对患者的应激状态进行评估。结果显示五音疗法可以改善患者的氧化应激状态。恶心呕吐标准评分、血常规和细胞免疫测定结果表明五音疗法可以改善患者的恶心呕吐症状,提高患者的免疫力,但是没有改善患化疗后出现的骨髓抑制。通过对患者生活质量评分表、焦虑抑郁量表对患者的生活质量和心理状态进行评估,结果表明五音疗法可以改善患者的生活质量和焦虑抑郁的不良情绪。结论:中医五音疗法可以通过改善乳腺癌患者的高氧化应激水平,缓解恶心呕吐症状和焦虑抑郁情绪,提高患者的免疫力,从而提高了患者化疗耐受力,减轻了毒副反应。
[Abstract]:Objective: to observe the effect of five tone therapy on stress state of breast cancer patients during chemotherapy. To explore the intervention mechanism of non-drug therapy on stress state of breast cancer patients during chemotherapy. Patients who met the inclusion criteria were divided into two groups: the treatment group (20 cases), Listening to music with headphones while chemotherapy and basic therapy, once a day, once in the afternoon, 2 courses of 20min for 21 days as a course of treatment, 20 cases in the control group, 20 cases in the control group, 20 cases in the control group, 20 cases in the control group, Before the first chemotherapy and the day before the 2nd and the next chemotherapy cycle, the curative effect was evaluated on the 2nd day of chemotherapy and the 4th day after chemotherapy. The side effects of chemotherapy and the score of stress state symptom were compared between the two groups. Quality of life assessment, psychological score, white blood cell count, platelet count, nitric oxide, superoxide dismutase, cellular immunity. Results: after the experiment, There were 20 effective cases in the experimental group and the control group. The results were as follows: the stress state observation table, nitric oxide (no) and superoxide dismutase (SOD) were used in the experiment. The results showed that the five tone therapy could improve the oxidative stress state of the patients. The scores of nausea and vomiting standard, blood routine and cellular immunoassay showed that the five tone therapy could improve the nausea and vomiting symptoms of the patients. To improve the immunity of patients, but not to improve the bone marrow suppression after chemotherapy. The quality of life and mental state of patients were evaluated by rating scale of quality of life and anxiety and depression scale. The results show that five tone therapy can improve the quality of life and anxiety and depression of patients. Conclusion: traditional Chinese medicine can improve the high level of oxidative stress in patients with breast cancer, relieve nausea and vomiting symptoms and anxiety and depression. Improve the patient's immunity, thus improve the patient's tolerance to chemotherapy, reduce the toxic side effects.
【学位授予单位】：南京中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R737.9

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