定量CT纹理分析鉴别诊断透明细胞型与非透明细胞型肾癌

发布时间：2018-04-02 04:17

本文选题：癌　切入点：肾细胞　出处：《中国医学影像技术》2017年12期

【摘要】：目的探讨定量CT纹理分析鉴别透明细胞型肾癌和非透明细胞型肾癌的可行性。方法回顾性分析100个透明细胞型肾癌和27个非透明细胞型肾癌病灶的CT图像,应用TexRAD软件分析各扫描期相两种类型肾癌的纹理特征。结果增强图像上,非透明细胞型肾癌的平均灰度值、标准差、熵、正像素的平均值明显低于透明细胞型肾癌,而峰度高于透明细胞型肾癌(P均0.001),偏度差异无统计学意义(P0.05)。在皮髓质期的粗糙纹理上,正像素的平均值鉴别两种类型肾癌的ROC曲线下面积为0.92±0.04,敏感度为0.85,特异度为0.93,准确率为0.87。结论透明细胞型肾癌与非透明细胞型肾癌的CT纹理特征间存在显著差异,定量CT纹理分析鉴别诊断这两种类型肾癌具有临床价值。
[Abstract]:Objective to study the feasibility of quantitative CT texture analysis in differentiating clear cell renal cell carcinoma from non-transparent cell renal cell carcinoma.Methods CT images of 100 clear cell renal cell carcinoma and 27 opaque cell renal cell carcinoma were analyzed retrospectively. The texture features of two types of renal cell carcinoma were analyzed by TexRAD software.Results the average gray value, standard deviation, entropy and positive pixel of non-transparent cell renal cell carcinoma were significantly lower than those of transparent cell renal cell carcinoma, but the kurtosis was higher than that of transparent cell renal cell carcinoma (P = 0.001), and there was no significant difference in bias (P 0.05).On rough texture of medullary phase, the area under ROC curve of positive pixel was 0.92 卤0.04, sensitivity was 0.85, specificity was 0.93and accuracy was 0.87.Conclusion there are significant differences in CT texture features between clear cell renal cell carcinoma and non-transparent cell renal cell carcinoma. Quantitative CT texture analysis is of clinical value in differential diagnosis of these two types of renal cell carcinoma.
【作者单位】：中国医学科学院北京协和医学院北京协和医院放射科;
【基金】：卫生部行业基金科研专项(201402019)
【分类号】：R730.44;R737.11

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