腹腔镜下子宫肌瘤剔除术对患者卵巢功能及血清创伤反应指标的影响

发布时间：2018-04-02 16:12

本文选题：子宫肌瘤　切入点：腹腔镜手术　出处：《山东医药》2017年06期

【摘要】：目的观察腹腔镜下子宫肌瘤剔除术对子宫肌瘤患者卵巢功能、血清疼痛指标及氧化损伤指标的影响。方法收集子宫肌瘤患者60例,其中行腹腔镜下子宫肌瘤剔除术30例(观察组),行开腹子宫肌瘤剔除术30例(对照组)。分别于术前及术后第1、3、6个月检测患者血清卵巢功能指标[雌二醇(E2)、黄体生成素(FSH)、促黄体生成素(LH)],于术前、术后第1、3、5天检测血清疼痛指标[心肌细胞P物质(SP)、白细胞介素6(IL-6)、前列腺素E2(PGE2)]及氧化损伤指标[肌红蛋白(MYo)、缺血修饰清蛋白(IMA)、八廓环磷酰胺(TAC)]。结果观察组术后第1、3、6个月血清E2水平高于对照组,而LH、FSH水平明显低于对照组(P均0.05);观察组术后第1、3、5天血清IL-6、SP、PGE2水平低于对照组(P均0.05);观察组术后第1、3、5天血清TAC水平高于对照组,而MYo、IMA水平低于对照组(P均0.05)。结论与开腹子宫肌瘤剔除术比较,腹腔镜下子宫肌瘤剔除术可减轻对子宫肌瘤患者卵巢功能及血清疼痛指标、氧化损伤指标的影响。
[Abstract]:Objective to observe the effects of laparoscopic hysteromyomectomy on ovarian function, serum pain and oxidative injury in patients with hysteromyoma.Methods A total of 60 patients with uterine leiomyoma were collected, 30 of them were treated with laparoscopic hysteromyomectomy (observation group) and 30 patients with open uterine myomectomy (control group).The serum ovarian function indexes (estradiol estradiol E2P, luteinizing hormone FSHO, luteinizing hormone (LH)) were measured before and after operation.The indexes of serum pain (substance P, interleukin-6 IL-6, prostaglandin E _ 2 PGE _ 2) and oxidative injury index (myoglobin MYoA, Ischemia modified albumin) were measured 5 days after operation.The level of MYoA was lower than that of control group (P < 0.05).Conclusion Laparoscopic hysteromyomectomy can reduce the effects of hysteromyomectomy on ovarian function, serum pain and oxidative injury in patients with hysteromyoma.
【作者单位】：云南省第一人民医院;
【分类号】：R737.33

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