原发性肾鳞状细胞癌2例病例报告并文献复习

发布时间：2018-04-04 09:22

本文选题：肾肿瘤　切入点：鳞状细胞癌　出处：《重庆医科大学》2017年硕士论文

【摘要】：目的总结原发性肾鳞状细胞癌的临床和病理特征,分析肾鳞状细胞癌容易误诊的原因,提高对肾鳞状细胞癌的诊治水平。方法回顾性分析2例被误诊的原发性肾鳞状细胞癌病例的临床、病理资料,并结合文献分析其常见病因、发病机制、临床表现及诊治。结果病例1行左肾及部分左侧输尿管切除术,病理结果提示:左肾盂鳞癌,癌细胞侵犯输尿管断端。病例2行根治性右肾肿瘤切除术,术后病理结果提示:右肾高分化的鳞状细胞癌,右肾肾周脂肪发现鳞癌细胞,肾盂及输尿管未见累及。2例术后均未行放疗、化疗,病例1术后3月死于癌细胞转移,病例2术后4月死于癌细胞转移。结论原发性肾脏鳞状细胞癌临床少见,患者早期多无明显临床症状,无明显包块的鳞状细胞癌影像学并不敏感,输尿管镜及软镜下取组织活检也有一定局限性,临床上容易漏诊、误诊。
[Abstract]:Objective to summarize the clinical and pathological features of primary renal squamous cell carcinoma (RSCC), to analyze the causes of misdiagnosis of RSCC, and to improve the diagnosis and treatment of renal squamous cell carcinoma (RSCC).Methods the clinical and pathological data of 2 misdiagnosed cases of primary renal squamous cell carcinoma were analyzed retrospectively. The common etiology, pathogenesis, clinical manifestation, diagnosis and treatment were analyzed in combination with literature.Results in case 1, the left kidney and part of the left ureterectomy were performed. The pathological results showed that the carcinoma of the left renal pelvis invaded the broken end of the ureter.Case 2 underwent radical resection of right renal tumor. The pathological results showed that: squamous cell carcinoma of the right kidney was well differentiated, squamous cell carcinoma was found in perirenal fat of the right kidney, no involvement of renal pelvis and ureter was observed in 2 cases, no radiotherapy and chemotherapy were performed after operation.Case 1 died of cancer metastasis 3 months after operation and case 2 died of cancer metastasis 4 months after operation.Conclusion Primary renal squamous cell carcinoma is rare in clinical practice. Most of the patients have no obvious clinical symptoms in the early stage. The imaging of squamous cell carcinoma without obvious mass is not sensitive, and biopsy under ureteroscope and soft microscope has some limitations.It is easy to miss diagnosis and misdiagnose clinically.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R737.11

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