前列腺癌实验室诊断方法研究进展

发布时间：2018-04-05 23:32

  本文选题：前列腺癌　切入点：实验室诊断　出处：《中华男科学杂志》2017年04期

【摘要】：近年来前列腺癌的发病率呈上升趋势,是导致患恶性肿瘤男性死亡的主要原因之一,其早期症状不明显,20%的患者初诊时已发生转移。早期诊断率低是我国前列腺癌病死率高于欧美国家的主要原因。前列腺癌患者的血液、尿液、精液中存在着特异性和敏感性较高的诊断标志物,如早期前列腺癌抗原、ERG蛋白、基质金属蛋白酶9、GSTP1甲基化等,联合检测可以提高前列腺癌早期诊断率,做到早发现、早治疗,为患者的治疗提供机会,进一步延长患者的生存期。
[Abstract]:In recent years, the incidence of prostate cancer is on the rise, which is one of the main causes of death in men with malignant tumor.The low early diagnosis rate is the main reason that the fatality rate of prostate cancer in China is higher than that in Europe and America.In the blood, urine and semen of prostate cancer patients, there are some specific and sensitive diagnostic markers, such as early prostate cancer antigen ERG protein, matrix metalloproteinase 9 GSTP1 methylation, etc.Combined detection can improve the rate of early diagnosis of prostate cancer, early detection, early treatment, for the treatment of patients with opportunities to further prolong the survival of patients.
【作者单位】： 天津中医药大学第一附属医院肿瘤科;
【基金】：天津市卫生局课题(13081) 天津市科学技术委员会科技支撑计划项目(12ZCDZSY17000)~~
【分类号】：R737.25
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本文编号：1717011