成人肝母细胞瘤1例报道并国内文献资料分析

发布时间：2018-04-06 01:20

  本文选题：成人　切入点：肝母细胞瘤　出处：《中国普外基础与临床杂志》2015年02期

【摘要】：目的报道我院1例诊断为成人肝母细胞瘤的病例,并检索国内文献,收集其随访资料,对其进行单因素及多因素分析,以探讨影响成人肝母细胞瘤的预后因素,为治疗提供参考。方法回顾性分析我院收治的1例及检索国内文献报道的41例成人肝母细胞瘤患者的临床资料,使用SPSS 19.0软件进行统计分析,采用KaplanMeier法计算生存率及中位生存时间,进行单因素分析;各因素亚组间生存分析比较采用log-rank检验,对差异统计学意义的因素进行Cox回归分析。结果 Log-rank检验证实,发病年龄≥70岁、多发肿瘤、姑息性治疗、病理学检测结果为胚胎型者生存率明显降低(P0.05);Cox多因素分析并未发现其独立危险因素。结论成人肝母细胞瘤的病理组织学类型、肿瘤数目及治疗方式可能是影响肝母细胞瘤患者预后的危险因素,有待进一步积累大样本量证实。
[Abstract]:Objective to report a case of adult hepatoblastoma diagnosed in our hospital, and to search the domestic literature, collect the data of follow-up, and make univariate and multivariate analysis to explore the prognostic factors of adult hepatoblastoma.To provide a reference for treatment.Methods the clinical data of 41 adult patients with hepatoblastoma were retrospectively analyzed and analyzed by SPSS 19.0 software. The survival rate and median survival time were calculated by KaplanMeier method.Univariate analysis and survival analysis among subgroups were carried out by log-rank test. Cox regression analysis was performed on the factors with statistical significance.Results the age of onset 鈮，

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