肺癌化疗患者医院感染病原学特征研究

发布时间：2018-04-09 01:18

  本文选题：肺癌化疗　切入点：医院感染　出处：《中国消毒学杂志》2017年02期

【摘要】：目的研究住院肺癌化疗患者医院感染病原学特征及相关危险因素,为有效防控提供科学依据。方法通过前瞻性研究方法,对某肿瘤医院内科住院肺癌化疗患者医院感染与感染病原菌特征进行观察,分析相关危险因素。结果该医院肿瘤内科共纳入肺癌化疗患者1 530例,发生医院感染56例,感染率3.66%。从56例感染患者送检标本中共分离病原菌74株,其中革兰阴性菌45株、革兰阳性菌16株和真菌13株。除真菌之外,所分离的病原菌均普遍耐药,尚未检出耐碳青霉烯类和耐万古霉素菌株。多因素分析显示,住院时间≥14 d、化疗周期≥2周和大量预防性使用抗菌药物等构成肺癌化疗患者医院感染的独立危险因素。结论肺癌化疗患者医院感染病原菌以革兰阴性菌为主,且耐药情况严重,缩短化疗周期和严格抗菌药物使用为主要防控措施。
[Abstract]:Objective to study the etiological characteristics and related risk factors of nosocomial infection in lung cancer patients with chemotherapy, and to provide scientific basis for effective prevention and control.Methods the characteristics of nosocomial infection and pathogenic bacteria in lung cancer patients treated with chemotherapy in a tumor hospital were observed and the risk factors were analyzed.Results A total of 1 530 lung cancer patients were included in the department of oncology in this hospital, 56 cases of nosocomial infection occurred, and the infection rate was 3.66%.A total of 74 pathogenic bacteria were isolated from 56 infected patients, including 45 Gram-negative bacteria, 16 Gram-positive bacteria and 13 fungi.With the exception of fungi, the isolated pathogens were generally resistant to drugs, and no carbapenem resistant strains and vancomycin resistant strains were detected.Multivariate analysis showed that hospital stay 鈮，

本文编号：1724204