养正消积胶囊联合XELOX方案治疗晚期胃癌临床观察

发布时间：2018-04-09 02:17

本文选题：晚期胃癌　切入点：XELOX方案　出处：《中华肿瘤防治杂志》2017年12期

【摘要】：目的胃癌是最常见的消化道恶性肿瘤之一,发病率和死亡率均位居前列,对人类健康构成严重威胁。本研究探讨养正消积胶囊联合XELOX方案治疗晚期胃癌的临床效果。方法选取2014-06-01-2016-06-30就诊于威海市立医院化疗科晚期胃癌患者60例。随机分为治疗组和对照组,分别采用养正消积胶囊联合XELOX方案(奥沙利铂+卡培他滨)与XELOX方案治疗,2个周期后比较临床治疗效果。结果治疗组患者治疗有效率为53.3%,对照组为43.3%,两组比较差异无统计学意义(P0.05);KPS改善率优于对照组,差异有统计学意义(P0.05);不良反应(胃肠道反应)的发生率低于对照组,差异有统计学意义(P0.05)。结论养正消积胶囊联合XELOX方案治疗晚期胃癌可明显降低治疗过程中不良反应的发生率,提高患者的生活质量。
[Abstract]:Objective gastric cancer is one of the most common malignant tumors of digestive tract.This study was to investigate the clinical effect of Yangzhengxiaoji capsule combined with XELOX regimen in the treatment of advanced gastric cancer.Methods 60 patients with advanced gastric cancer were selected from 2014-06-01-2016-30 in the Department of chemotherapy of Weihai City Hospital.The treatment group and control group were randomly divided into two groups: Yangzheng Xiaoji capsule combined with XELOX regimen (oxaliplatin capecitabine) and XELOX regimen.Results the effective rate of treatment was 53.3% in the treatment group and 43.3% in the control group. There was no significant difference between the two groups in the improvement rate of KPS, the difference was statistically significant (P 0.05), and the incidence of adverse reactions (gastrointestinal tract reaction) was lower than that in the control group.The difference was statistically significant (P 0.05).Conclusion Yangzheng Xiaoji capsule combined with XELOX regimen can significantly reduce the incidence of adverse reactions and improve the quality of life of patients with advanced gastric cancer.
【作者单位】：威海市立医院化疗科;威海市立医院门诊部;
【分类号】：R735.2

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