抗抑郁药防治神经胶质瘤的相关性研究进展

发布时间：2018-04-19 06:48

本文选题：抑郁症 + 神经胶质瘤　；参考：《国际药学研究杂志》2017年08期

【摘要】：神经胶质瘤与抑郁症同属脑部疾病范畴,两者之间存在着一定的相关性。在治疗神经胶质瘤过程中,常伴发抑郁症,而抑郁症的发生非常不利于神经胶质瘤的治疗。通过检索大量国内外文献发现,有运用抗抑郁药治疗或辅助性治疗神经胶质瘤的报道,但其作用机制尚不明确。本文通过分析抑郁症与神经胶质瘤的临床特征、病理特征及中医理论的关联性,综述了抗抑郁相关药物防治神经胶质瘤的机制研究进展,旨在为胶质瘤治疗药物筛选提供一定参考,为神经胶质瘤的防治提供新思路。
[Abstract]:Glioma and depression belong to the category of brain diseases, there is a certain correlation between them.In the treatment of glioma, often accompanied by depression, and depression is not conducive to the treatment of glioma.By searching a large number of literatures at home and abroad, it is found that there are reports of antidepressant therapy or adjuvant therapy for glioma, but the mechanism of action is still unclear.This article reviews the mechanism of antidepressant drugs in the prevention and treatment of glioma by analyzing the clinical characteristics, pathological characteristics and the correlation of TCM theory with depression.The aim is to provide some reference for the screening of glioma therapy drugs and a new idea for the prevention and treatment of glioma.
【作者单位】：江西中医药大学创新药物与高效节能降耗制药设备国家重点实验室;江西中医药大学中药固体制剂制造技术国家工程研究中心;成都中医药大学;
【基金】：江西省普通本科高校中青年教师发展计划访问学者专项资金项目资助(20123BBG70201)
【分类号】：R739.41

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