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2013年-2016年广西医科大学第一附属医院非小细胞肺癌患者人群特征分析

发布时间:2018-05-02 00:09

  本文选题:非小细胞肺癌 + 人群特征 ; 参考:《广西医科大学》2017年硕士论文


【摘要】:目的:肺癌是我国常见的恶性肿瘤之一,其中以非小细胞肺癌多见。本研究通过对2013年至2016年于广西医科大学第一附属医院住院的非小细胞肺癌患者的人群特征进行回顾性分析,以初步了解近年来非小细胞肺癌的人群特点。方法:收集2013年至2016年于广西医科大学第一附属医院住院的非小细胞肺癌患者住院病例,对其中的男女比例、年龄分布、病人来源、吸烟史、民族、病理类型、临床分期等临床资料进行对比分析。结果:收集非小细胞肺癌病例共2,564例,其中2013年568例,2014年635例,2015年669例,2016年692例。男性患者1,699例,女性患者865例,男女比例为1.96:1。年龄段在50-59岁的患者最多,为828例,占32.29%。女性患者在该年龄段病例数最多,为277例,占女性患者病例数的32.02%。男性患者在60-69岁年龄段最多,为571例,占男性患者病例数的33.61%。非小细胞肺癌患者以腺癌最多见,在各病理类型中占71.41%。腺癌在2013年-2016年的构成比分别是:67.61%、71.81%、70.85%、74.71%。腺癌患者的男女构成比为59.64%,40.36%,鳞癌患者的男女构成比为85.16%,14.84%。腺癌于各年龄段中构成比分别为81.05%、72.67%、71.50%、70.05%、66.44%、86.67%。2,564例非小细胞肺癌患者中,吸烟患者为1,207例(47%),非吸烟患者1,357例(53%)。吸烟与非吸烟患者中,病理类型均以腺癌多见,吸烟者中的腺癌病例为708例(58.66%),非吸烟患者中的腺癌病例为1123例(82.76%)。壮族患者中以腺癌居多,占74.39%。广西地区患者多数来自南宁,占30.89%,病理类型以腺癌为主。在具有明确TNM分期及临床分期的1,931例非小细胞肺癌患者中,临床分期为Ⅲb、Ⅳ期的病例数最多,为1,205例,占62.40%。结论:近四年于我院住院的确诊为非小细胞肺癌患者呈现逐年增多趋势,其中以男性患者多见,中老年患者居多,大多数病人确诊时已处于晚期。在本研究的非小细胞肺癌患者中,病理类型以腺癌为主,占71.41%,其构成比大致呈现逐年升高趋势。吸烟与非吸烟患者中,病理类型均以腺癌多见。吸烟患者的鳞癌患者构成比高于非吸烟患者,提示吸烟与鳞癌关系密切。壮族非小细胞肺癌患者中以腺癌居多,病理类型分布与汉族患者相比存在明显差异。
[Abstract]:Objective: lung cancer is one of the most common malignant tumors in China. In this study, the population characteristics of non-small cell lung cancer (NSCLC) patients hospitalized in the first affiliated Hospital of Guangxi Medical University from 2013 to 2016 were analyzed retrospectively to understand the population characteristics of NSCLC in recent years. Methods: the inpatients with non-small cell lung cancer (NSCLC) hospitalized in the first affiliated Hospital of Guangxi Medical University from 2013 to 2016 were collected. The male and female ratio, age distribution, patient origin, smoking history, ethnicity, pathological type of NSCLC were analyzed. The clinical data such as clinical staging were compared and analyzed. Results: 2564 cases of NSCLC were collected, including 568 cases in 2013, 635 cases in 2014, 669 cases in 2015 and 692 cases in 2016. There were 1699 males and 865 females, with a ratio of 1.96: 1. Patients aged 50-59 years were the most, 828 cases (32.29%). The largest number of female patients in this age group, 277 cases, accounted for 32. 02% of female cases. Male patients were the most in the 60-69 age group, accounting for 571 cases, accounting for 33.61% of male cases. Adenocarcinoma is the most common type of non-small cell lung cancer, accounting for 71. 41% of the pathological types. The constitution of adenocarcinoma in 2013-2016 is: 67.61 / 71.81 / 70.85 / 74.71 respectively. The ratio of male to female was 59.64% in adenocarcinoma and 14.84 in squamous cell carcinoma. The constituent ratio of adenocarcinoma in each age group was 81.05 and 71.50 respectively. The ratio of 70.055.66.44and 86.67.2564 cases of non-small cell lung cancer was 86.67.2564, of which 1207 were smoking patients and 1357 were non-smoking patients. Adenocarcinoma was the most common pathological type in smoking and non-smoking patients. There were 708 cases of adenocarcinoma in smokers and 1123 cases of adenocarcinoma in non-smoking patients. The majority of Zhuang patients were adenocarcinoma (74.39%). Most of the patients in Guangxi were from Nanning (30.89%), and adenocarcinoma was the main pathological type. Among the 1931 cases of non-small cell lung cancer with definite TNM staging and clinical staging, the clinical stage 鈪,

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