手辅助腹腔镜与腹腔镜辅助手术治疗结直肠癌的对比研究

发布时间：2018-05-02 14:20

本文选题：结直肠癌 + 手辅助腹腔镜　；参考：《西安交通大学学报(医学版)》2017年01期

【摘要】：目的比较手辅助腹腔镜与腹腔镜辅助手术在外科治疗结直肠癌中的近期疗效,评估手辅助腹腔镜外科治疗结直肠癌的安全性及对全身应激炎症的影响。方法选取2012年9月-2016年3月收治的100例结直肠癌患者,按照随机数字表法分为腹腔镜辅助治疗组(A组,n=63)与手辅助腹腔镜治疗组(B组,n=37),对比两组手术相关指标、术后并发症及全身应激炎症反应水平。结果 B组在手术时间、手术出血量、引流量均优于A组(P0.05),排气时间较A组长(P0.05)。两组术后住院时间及术后并发症发生率的差异无统计学意义(P0.05)。B组全身应激炎症反应指标中性粒细胞数和C反应蛋白(CRP)与A组差异无统计学意义(P0.05),而B组血清中炎症因子白细胞介素-6(IL-6)水平高于A组水平,差异有统计学意义(P0.05)。结论在结直肠癌治疗中,手辅助腹腔镜手术具有手术时间短、术中出血量低等优点,但腹腔镜辅助手术在术后胃肠功能恢复方面更具优势,手辅助腹腔镜手术的全身炎症因子IL-6水平高于腹腔镜组,在临床应用时应依据实际情况合理选取腹腔镜手术术式。
[Abstract]:Objective to compare the efficacy of hand-assisted laparoscopy and laparoscopy-assisted surgery in the surgical treatment of colorectal cancer, and to evaluate the safety of hand-assisted laparoscopic surgery in the treatment of colorectal cancer and its effect on systemic stress inflammation. Methods from September 2012 to March 2016, 100 patients with colorectal cancer were randomly divided into two groups: group A (group A) and group B (group B). Postoperative complications and systemic stress inflammatory response. Results in group B, the operation time, blood loss and drainage volume were better than that in group A (P 0.05), and the exhaust time was higher than that in group A (P 0.05). There was no significant difference in the length of hospitalization and the incidence of postoperative complications between the two groups. There was no significant difference in the number of neutrophils and C-reactive protein (CRP) between group B and group A, but there was no significant difference between group B and group A in serum inflammation. The level of interleukin-6 (IL-6) was higher in group A than that in group A. The difference was statistically significant (P 0.05). Conclusion Hand-assisted laparoscopic surgery has the advantages of short operation time and low intraoperative bleeding in the treatment of colorectal cancer, but laparoscopic assisted surgery has more advantages in the recovery of gastrointestinal function after operation. The level of systemic inflammatory factor (IL-6) in hand-assisted laparoscopic surgery was higher than that in laparoscopic group.
【作者单位】：西安交通大学第一附属医院普通外科;西安交通大学第二附属医院肿瘤外科;西安交通大学第一附属医院麻醉科;
【基金】：陕西省科技攻关项目(No.2012K13-01-05)~~
【分类号】：R735.34

【相似文献】