延边地区青年肺癌发病趋势分析

发布时间：2018-05-11 12:27

本文选题：延边地区 + 青年　；参考：《延边大学》2015年硕士论文

【摘要】：目的：研究延边地区男、女青年肺癌患者的发病情况,分析其发病率趋势。为防治本地区青年肺癌患者提供基本资料。方法：利用延边大学附属医院病历档案室电子病例系统输入的1995年1月1日至2014年12月31日医院收治的青年肺癌新发病例资料,按每5年为一个时期,按其性别、年龄、地区分布及不同的病理学分型,计算其粗发病率、截缩率和累计率及居住地等情况进行对比分析。结果：男性青年肺癌的构成比及调整发病率均略减低,粗发病率逐年上升(由1991-1995年间的8.37/10万上升至2010-2014年的12.8/10万)；女性青年肺癌构成比及粗发病率上升(粗发病率由8.37/10万上升至11.0/10万,但调整发病率由10.38/10万下降至6.0/10万)；男性35-64岁截缩率逐渐升高,由10.38/10万升至15.50/10万,女性35-64岁截缩率由10.38/10万上升为13.7/10万,0-64岁累积率逐渐增高,由51.9/10万上升至68.3/10万。青年男、女患者的鳞癌及小细胞癌构成比略下降,而青年男、女患者的腺癌的发病率呈上升趋势；青年男、女肺癌患者有吸烟史的构成比明显高于不吸烟者；居住地在农村的青年男、女肺癌患者构成比明显高于市区。朝族与汉族患者发病情况无明显差异。结论：1.延边地区青年女性肺癌中,鳞癌及小细胞癌构成比逐年下降,腺癌的构成比呈逐年上升趋势,男患无显著变化。其病理学类型构成变化与多数发达国家的流行特征基本相符。2.延边地区男、女青年肺癌粗发病率、35-64岁截缩率及0-64岁积累率均明显上升,但调整发病率逐年下降；发病频数最高的为40岁组。青年女性患者的别发病率呈逐年增高,且显著高于男性。与2009年全国恶性肿瘤监测肺癌发病率呈现持续上升趋势结果相一致。3.青年男、女肺癌患者有吸烟史的构成比明显高于不吸烟者；居住地在农村的青年男、女肺癌患者构成比明显高于市区。且女性患者发病率相差悬殊。与我国其他地区发病趋势类似。朝、汉族患者发病构成比无显著差异。
[Abstract]:Objective: to study the incidence of lung cancer in young men and women in Yanbian area. To provide basic data for prevention and treatment of young lung cancer patients in this area. Methods: the data of young patients with lung cancer admitted from January 1, 1995 to December 31, 2014 were recorded by electronic case system in the medical records of Yanbian University affiliated Hospital. According to the period of 5 years, according to their sex and age. The regional distribution and different pathological types were compared and analyzed by calculating the crude incidence rate, truncation rate, cumulative rate and place of residence. Results: the constitution ratio and adjusted incidence rate of lung cancer in young men decreased slightly. The crude incidence rate increased year by year (from 8.37% / 100,000 in 1991-1995 to 12.8% / 100,000 in 2010-2014), and the proportion of lung cancer in young women and the crude incidence rate increased (from 8.37% / 100 000 to 110% / 100 000, respectively). But the adjusted incidence rate dropped from 10.38 / 100 million to 6.0 / 100, 000; the truncation rate of 35-64 years in men gradually increased, from 10.38 / 100 million to 1550 / 100, 000; in women, the rate of truncation in 35-64 years increased from 10.38 / 100 million to 13.7 / 100,000 to 68.3 / 100 million years old, from 519.1 / 100 million to 68.3 / 100 thousand. The proportion of squamous cell carcinoma and small cell carcinoma in young male and female patients decreased slightly, while the incidence of adenocarcinoma in young male and female patients showed an increasing trend, the proportion of young male and female lung cancer patients with smoking history was obviously higher than that of non-smoker. The constitution ratio of young men and women with lung cancer in rural areas was significantly higher than that in urban areas. There was no significant difference in the incidence between Korean and Han nationality. Conclusion 1. In young female lung cancer in Yanbian area, the proportion of squamous cell carcinoma and small cell carcinoma decreased year by year, and that of adenocarcinoma increased year by year, but there was no significant change in male lung cancer. The change of pathological type composition is basically consistent with the epidemic characteristics of most developed countries. 2. 2. In Yanbian area, the incidence rate of lung cancer in male and young women aged 35-64 years old and the accumulation rate of 0-64 years old increased obviously, but the adjusted incidence rate decreased year by year, and the highest incidence frequency was 40 years old group. The specific incidence rate of young women increased year by year and was significantly higher than that of men. The incidence rate of lung cancer in the surveillance of malignant tumor in China in 2009 is consistent with the results of the rising trend. 3. 3. The proportion of lung cancer patients with smoking history was significantly higher than that of non-smokers, while that of young men and women with lung cancer patients living in rural areas was significantly higher than that in urban areas. And the incidence of female patients varies greatly. The incidence trend is similar to that in other regions of China. There was no significant difference in morbidity ratio between Han and Korean patients.
【学位授予单位】：延边大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R734.2

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