宫颈细胞学正常的高危HPV感染妇女病理结局分析

发布时间：2018-05-20 07:27

  本文选题：宫颈细胞学检查 + 高危型HPV检测　； 参考：《现代妇产科进展》2017年02期

【摘要】：目的:探讨宫颈细胞学正常但高危型HPV感染妇女的宫颈病理结局。方法:回顾分析2014年1月~12月就诊于湖北省妇幼保健院妇科门诊的30岁以上行宫颈细胞学+Cervista高危型HPV联合筛查妇女的临床资料,对细胞学正常但高危型HPV感染且行阴道镜检查的218例妇女取活组织检查,分析其病理结局。结果:218例患者中,宫颈病变占27.5%(60/218),其中宫颈低级别鳞状上皮内病变占11.0%(24/218),宫颈高级别鳞状上皮内病变占13.8%(30/218),宫颈浸润癌占2.8%(6/218)。HPV A9组感染共141例,其中CINⅡ/Ⅲ及以上病变21.3%(30/141),HPV A9组阳性与A9组阴性者比较,CINⅡ/Ⅲ及以上病变检出率比较,差异有统计学意义(P0.05)。结论:即使细胞学检查阴性,对宫颈高危型HPV检测及阳性结果尤其是A9组阳性,应高度重视,立即行阴道镜检查以早期发现宫颈高级别鳞状上皮内病变及宫颈浸润癌。
[Abstract]:Objective: to investigate the cervical pathological outcome of women with normal cervical cytology but high risk HPV infection. Methods: the clinical data of women over 30 years old who were diagnosed in gynecological clinic of Hubei Maternal and Child Health Hospital from January to December 2014 were analyzed retrospectively. Women who underwent Cervista high-risk type HPV screening by cervical cytology were analyzed retrospectively. Biopsy of 218 women with normal cytology but high risk HPV infection and colposcopy was performed and the pathological outcome was analyzed. Results among the 218 cases, cervical lesions accounted for 27.5% of 60 / 218g, of which 11.0% were low grade squamous intraepithelial lesions, 13.88% 30 / 218C were cervical high-grade squamous intraepithelial lesions, 141 cases were cervical invasive carcinoma, and 141 cases were infected in 2.8%(6/218).HPV A9 group. The positive rate of CIN 鈪，

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