植入式静脉输液港相关感染并发症风险因素分析

发布时间：2018-06-07 18:48

本文选题：植入式静脉输液港 + 肿瘤患者　；参考：《介入放射学杂志》2016年11期

【摘要】：目的探讨植入式静脉输液港(IVAP)应用患者发生导管相关感染并发症的风险因素。方法收集2012年1月至2015年12月接受IVAP植入治疗的582例患者临床资料,对患者一般临床资料、细菌学资料、病情进展情况及IVAP相关感染发生率进行回顾性分析。结果 14例(2.4%,14/582)患者出现感染症状后取出IVAP,IVAP相关感染发生率为67例/千导管日。单因素分析显示住院患者(P=0.016)、恶性血液疾病患者(P=0.040)及接受姑息性化疗患者(P=0.022)感染率较高。多变量二元回归分析结果显示,恶性血液疾病及姑息性化疗患者发生感染的校正OR值分别为7.769(P=0.001)、4.863(P=0.003)。9例血液样本中细菌培养为阳性,最常见者为葡萄球菌(n=4)及念珠菌(n=2)。结论恶性血液病和姑息性化疗,可能是引起IVAP相关感染的独立危险因素。
[Abstract]:Objective to investigate the risk factors of complications of catheter-related infection in patients with IVAP. Methods the clinical data of 582 patients undergoing IVAP implantation from January 2012 to December 2015 were analyzed retrospectively. The general clinical data, bacteriological data, disease progression and the incidence of IVAP related infection were analyzed retrospectively. Results the incidence of IVAP associated infection in 14 / 582 patients with IVAPP was 67 / 1000 catheter days. Univariate analysis showed that the infection rates of P0. 016, P0. 040) and palliative chemotherapy patients were higher. The results of multivariate binary regression analysis showed that the corrected OR values of infection in patients with malignant blood diseases and palliative chemotherapy were 7.769%, 4.863% and 0.003% respectively, and the most common ones were Staphylococcus ntii 4) and Candida moniliformis. Conclusion malignant hematopathy and palliative chemotherapy may be independent risk factors for IVAP associated infection.
【作者单位】：贵州医科大学附属医院介入科;贵州省肿瘤医院介入科;四川省肿瘤医院介入科;
【基金】：国家自然科学基金(81560297)
【分类号】：R55

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