胰头部肿瘤姑息治疗方法探讨

发布时间：2018-06-14 16:51

本文选题：胰头部肿瘤 + 姑息治疗　；参考：《临床军医杂志》2016年11期

【摘要】：目的探讨不同条件下的胰头部肿瘤患者姑息治疗的方法及治疗效果。方法回顾性分析2005年1月至2015年12月在新疆医科大学第一附属医院收治的139例胰头部肿瘤患者的临床资料。根据患者的不同条件分为可切除组(45例)和不可切除组(94例),根据治疗方式不同将两组细分为姑息手术组和支架组,共4个亚组。通过对生存时间及术后1个月白蛋白、总胆红素、并发症等指标的观察和对比分析,评价可切除组和不可切除组姑息手术治疗的情况。结果本研究139例患者术后获随访9~36个月。可切除组与不可切除组患者在住院时间方面比较,差异无统计学意义(P0.05);而在生存时间及术后1个月白蛋白、总胆红素指标方面比较,差异有统计学意义(P0.05)。可切除组中,姑息手术组患者中位生存期大于支架组(P0.05);不可切除组中,姑息手术组患者中位生存期小于支架组(P0.05)。结论对于胰头部肿瘤可切除但放弃行胰十二指肠根治术者,治疗方案更倾向于姑息手术治疗;而对于不可切除者,治疗方案更倾向于支架治疗。
[Abstract]:Objective to investigate the methods and effect of palliative treatment of pancreatic head tumor patients under different conditions. Methods the clinical data of 139 patients with pancreatic head tumors admitted in the First Affiliated Hospital of Xinjiang Medical University from January 2005 to December 2015 were retrospectively analyzed. According to the different conditions, the patients were divided into excision group (45 cases) and non resectable group (94 According to the different treatment methods, two groups were divided into palliative operation group and stent group, 4 subgroups. Through observation and comparison of survival time and 1 months postoperatively albumin, total bilirubin, complications and other indexes, the treatment of excision group and unresectable group palliative treatment were evaluated. Results 139 patients were followed up 9 after operation. ~36 months. There was no significant difference in the time of hospitalization between the excision group and the non resectable group (P0.05), but there was a significant difference in the survival time and the total bilirubin index in the 1 months after the operation (P0.05). In the resectable group, the median survival time of the palliative group was greater than that of the stent group (P0.05); In the group, the median survival time of the patients in the palliative operation group was less than that of the stent group (P0.05). Conclusion the treatment scheme is more inclined to palliative surgery for the resection of the head of the pancreas but abandons the radical pancreatoduodenectomy, but for the non resectable, the treatment scheme is more inclined to the stent treatment.
【作者单位】：新疆医科大学第一附属医院胰腺外科;
【分类号】：R735.9

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