四磨汤口服液对食管癌术后胃肠功能影响的初步研究

发布时间：2018-06-22 14:24

本文选题：四磨汤口服液 + 食管癌术后　；参考：《广西医科大学》2017年硕士论文

【摘要】：目的:探讨四磨汤口服液对食管癌术后胃肠功能与胃肠激素分泌的影响。方法:选取70例食管癌手术患者随机分为四磨汤口服液组和生理盐水组各35例,两组均给予围手术期常规营养支持治疗。四磨汤口服液组术后经鼻肠营养管注入四磨汤口服液,生理盐水组给予等量生理盐水(安慰剂)治疗,观察比较两组患者胃肠功能恢复情况及胃肠激素分泌的影响。结果:四磨汤口服液组对于食管癌术后肠鸣音恢复时间、首次肛门排气时间均显著早于生理盐水组(P0.05),但两组首次肛门排便时间并无显著性差异(P0.05);四磨汤口服液组血浆MTL和GAS水平与生理盐水组间两两比较有显著性差异(P0.05);且两组MTL、GAS浓度术后随着时间推移呈现上升趋势,组内不同时间点水平差异均有统计学意义(P0.05)结论:四磨汤口服液能够有效促进食管癌术后胃肠功能的恢复,加速康复,可能与其促进MTL、GAS的分泌有关。
[Abstract]:Objective: To investigate the effect of simmotang oral liquid on gastrointestinal function and gastrointestinal hormone secretion after esophagus cancer operation. Methods: 70 cases of esophageal cancer were randomly divided into four milled oral liquid group and 35 normal saline group. The two groups were given perioperative routine nutritional support treatment. Four moortang oral liquid group was injected by naso enteral nutrition tube after operation four. In the two groups, the recovery of gastrointestinal function and the effect of gastrointestinal hormone secretion were compared between the two groups. Results: the time of the recovery of the bowel sounds after the operation of the esophagus carcinoma and the first anus exhaust time were significantly earlier than that of the normal saline group (P0.05), but the first two groups were first. There was no significant difference in the time of the anus defecation (P0.05). The plasma MTL and GAS levels were significantly different from those in the normal saline group (P0.05), and the concentration of MTL and GAS in the group of MTL and GAS increased with time, and the difference in the different time points in the group was statistically significant (P0.05). Fluid can effectively promote the recovery of gastrointestinal function after esophageal cancer surgery, and it may be related to the promotion of MTL and GAS secretion.
【学位授予单位】：广西医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R735.1

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