改良胰腺神经内分泌肿瘤分期的临床解读

发布时间：2018-06-22 15:15

本文选题：胰腺神经内分泌肿瘤 + 分期　；参考：《中国癌症杂志》2017年05期

【摘要】：胰腺神经内分泌肿瘤是一种常见的胰腺恶性肿瘤,异质性极强,诊治手段多样,因此,统一、实用的分期系统将有助于临床诊治及研究。目前,胰腺神经内分泌肿瘤包括欧洲神经内分泌肿瘤协会(European Neuroendocrine Tumor Society System,ENETS)和美国癌症联合委员会(American Joint Committee on Cancer,AJCC)两种分期,然而两种分期系统对临床指导价值有限,且两种分期系统的并存造成了分期系统混乱的局面。复旦大学附属肿瘤医院胰腺肝胆外科通过结合ENETS中TNM的定义及AJCC中分期的定义,建立了改良的分期系统,该分期能更好地区分出不同预后的人群,更适合于指导临床应用,有利于建立统一的临床分期标准。研究结果发表在《临床肿瘤学杂志》(Journal of Clinical Oncology,JCO)上。研究得到了国际同行的高度重视与认可,被评为"2017 Best of JCO:Gastrointestinal edition"。JCO编辑部进行了专篇述评。该研究就改良分期系统的临床应用进行解读。
[Abstract]:Pancreatic neuroendocrine tumor is a common pancreatic malignant tumor with strong heterogeneity and various methods of diagnosis and treatment. Therefore, a unified and practical staging system will be helpful for clinical diagnosis, treatment and research. At present, pancreatic neuroendocrine tumors include two stages, the European Neuroendocrine tumor Society system (ENETs) and the American Joint Committee on Cancer (AJCC). However, the two staging systems are of limited clinical value. And the coexistence of the two staging systems caused chaos in the staging system. By combining the definition of TNM in ENETs and the definition of staging in AJCC, an improved staging system was established in the Pancreatic Hepatobiliary surgery of the affiliated Cancer Hospital of Fudan University. It is helpful to establish a unified clinical staging standard. The results were published in the Journal of Clinical Oncology (JCO). The research has been highly valued and recognized by international peers, and has been appraised as "2017 Best of JCO: Gastrointestinal edition" .JCO editorial Department has made a special review. This study interprets the clinical application of the modified staging system.
【作者单位】：复旦大学附属肿瘤医院胰腺肝胆外科复旦大学上海医学院肿瘤学系;
【分类号】：R735.9

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