cN0甲状腺乳头状癌对侧中央区淋巴结转移相关因素的探讨

发布时间：2018-06-23 23:09

  本文选题：甲状腺乳头状癌 + 对侧中央区淋巴结　； 参考：《中国肿瘤临床》2017年01期

【摘要】：目的:分析c N0甲状腺乳头状癌(papillary thyroid carcinoma,PTC)对侧中央区淋巴结(contralateral central lymph nodes,Cont-CLNs)转移相关因素,探讨Cont-CLNs清扫适应证。方法:回顾性分析2013年6月至2015年12月就诊于重庆医科大学附属第一医院的单侧PTC患者149例,均已接受甲状腺全切以及预防性Cont-CLNs清扫。分析性别、年龄、肿瘤直径、包膜外侵犯、原发灶数目、是否合并甲状腺炎、喉前淋巴结、Ipsi-CLNs与Cont-CLNs转移的关系。结果:本组患者Ipsi-CLNs转移率和Cont-CLNs转移率分别为73.2%和23.5%,其中性别、年龄、肿瘤直径、原发灶数目、是否合并甲状腺炎与Cont-CLNs转移均不相关(P=0.792、0.097、0.531、0.578、0.269、1.000),包膜外侵犯(P=0.017)、喉前淋巴结转移(P=0.006)和Ipsi-CLNs转移(P0.001)与Cont-CLNs转移相关。但多因素分析后发现Ipsi-CLNs转移数目≥3枚是Cont-CLNs转移的独立危险因素(P=0.010)。结论:包膜外侵犯、喉前淋巴结和Ipsi-CLNs是Cont-CLNs的影响因素;当Ipsi-CLNs转移数目≥3枚,且合并喉前淋巴结或包膜外侵犯时,可考虑行ContCLNs清扫。
[Abstract]:Objective: to analyze the factors related to the metastasis of (papillary thyroid carcinomatous carcinoma (papillary thyroid) in the contralateral central lymph node of c N0 thyroid papillary carcinoma, and to explore the indications for the dissection of Cont-CLNs. Methods: from June 2013 to December 2015, 149 patients with unilateral PTC who were admitted to the first affiliated Hospital of Chongqing Medical University were retrospectively analyzed. All patients underwent total thyroidectomy and prophylaxis Cont-CLNs dissection. To analyze the relationship between sex, age, tumor diameter, extracapsular invasion, number of primary lesions, thyroiditis, Ipsi-CLNs in prelaryngeal lymph nodes and Cont-CLNs metastasis. Results: the metastatic rates of Ipsi-CLNs and Cont-CLNs were 73.2% and 23.5in this group respectively. There was no correlation between concomitant thyroiditis and Cont-CLNs metastasis (P0. 792 0. 097 0. 571), extracapsular invasion (P0. 017), prelaryngeal lymph node metastasis (P0. 006) and Ipsi-CLNs metastasis (P0. 001) associated with Cont-CLNs metastasis. However, multivariate analysis showed that the number of Ipsi-CLNs metastasis 鈮，

本文编号：2058833