甲状腺乳头状癌中央区淋巴结转移风险预测及危险分层

发布时间：2018-06-23 23:30

  本文选题：甲状腺乳头状癌 + 淋巴结转移　； 参考：《实用医学杂志》2017年22期

【摘要】：目的构建甲状腺乳头状癌(PTC)中央区淋巴结转移(CLNM)风险评估量表并进行危险分层。方法回顾性分析北京世纪坛医院2010年1月至2015年6月术后病理证实为PTC的502例患者的资料,明确CLNM的独立危险因素,建立风险评估量表并进行危险分层,评估量表的预测价值,之后收集2015年7月至2016年6月术后病理证实为PTC的100例患者的资料对量表进行验证。结果选取5分作为CLNM的最佳诊断界值,其灵敏度和特异性分别为73.8%和70.2%,≤4.5分CLNM风险为低危,5.0~7.0分为中危,≥7.5分为高危。使用其余100例病例对量表进行验证,灵敏度为79.5%,特异性为78.7%,阳性预测值70.5%,阴性预测值85.7%。结论 CLNM风险评估量表对评估CLNM风险提供了一个简便、直观的量化指标,更有利于制定个体化治疗方案、减少术后并发症的发生概率。
[Abstract]:Objective to construct a risk assessment scale for central lymph node metastasis (CLNM) in papillary thyroid carcinoma (PTC). Methods the data of 502 patients with PTC confirmed by pathology from January 2010 to June 2015 in Beijing Shijitan Hospital were retrospectively analyzed. The independent risk factors of CLNM were determined, and the risk assessment scale was established and stratified to assess the predictive value of the scale. From July 2015 to June 2016, 100 patients with postoperative pathologically confirmed PTC were collected to verify the scale. Results the sensitivity and specificity of CLNM were 73.8% and 70.2%, respectively. The risk of CLNM 鈮，

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