腹腔镜下保留盆腔神经宫颈癌根治术对膀胱功能影响的研究

发布时间：2018-07-14 20:42

【摘要】：目的探讨腹腔镜下保留盆腔神经的宫颈癌根治术(LNSRH)对患者膀胱功能及短期肿瘤治疗的临床意义及该术式适用人群。方法 2013年7月至2015年11月上海交通大学医学院附属仁济医院收治的宫颈癌患者219例,150例行LNSRH术,69例行腹腔镜下宫颈癌根治术(LRH),组间比较围手术期一般情况及留置导尿管时间,组内比较尿动力学检查及膀胱自我感觉等指标。结果 LNSRH组手术时间短于LRH组[(153±42)min vs.(210±92)min,P0.05],余围手术期一般情况未发现明显差异;LNSRH组术后留置导尿管时间短于LRH组(14 d vs.20 d,P=0.006);LNSRH组患者在术后最大尿流率、残余尿量、初始尿意膀胱容量、最大尿意膀胱容量及逼尿肌收缩等尿动力学方面恢复均优于LRH组;LNSRH组患者在术后膀胱自我感觉指标达到术前水平的时间均短于LRH组。结论 LNSRH对膀胱功能影响较小且术后膀胱功能恢复较快。
[Abstract]:Objective to investigate the clinical significance of laparoscopic radical resection of cervical carcinoma (LNSRH) for bladder function and short term tumor therapy. Methods from July 2013 to November 2015, 219 patients with cervical cancer treated in Renji Hospital, School of Medicine, Shanghai Jiaotong University, were treated with LNSRH and 69 patients underwent laparoscopic radical cervical cancer resection (LRH). The general situation of perioperative period and the time of indwelling urethral catheter were compared between the two groups. Urodynamic examination and bladder self-perception were compared in the group. Results the operative time of LNSRH group was shorter than that of LRH group [(153 卤42) min vs. (210 卤92) min P0.05]. There was no significant difference in the rest perioperative period. The time of indwelling catheter in LNSRH group was shorter than that in LRH group (14 d vs.20 DX P0. 006). The recovery of maximal urinary bladder volume and detrusor contraction was better than that of LRH group. The time of bladder self-feeling was shorter in LRH group than in LRH group. Conclusion LNSRH has little effect on bladder function and recovery of bladder function after operation.
【作者单位】：上海交通大学医学院附属仁济医院妇科肿瘤科;
【基金】：上海市市级医院新兴前沿技术联合攻关项目任务书(编号:SHDC12014115)
【分类号】：R737.33

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