胃神经内分泌肿瘤的诊断及治疗
发布时间：2018-07-30 07:37
【摘要】：目的通过对74例胃神经内分泌肿瘤的发病、诊断、治疗和预后的研究,进一步加深对胃神经内分泌肿瘤的了解,提高胃神经内分泌肿瘤的诊治水平方法回顾性分析2008年1月至2013年9月安徽医科大学第一附属医院收治的74例胃神经内分泌肿瘤患者的临床资料和随访结果,数据通过SPSS 16.0软件处理,采用Kaplan-Meier法进行单因素生存分析.结果74例胃神经内分泌肿瘤患者,平均年龄为62.86岁,男女比例2.52：1；首发症状以上腹不适为主的有48例(约占64.86%),进食哽噎有21例(约28.38%),反酸暖气、黑便、消瘦等症状的有12例(约占16.21%)。74例患者中,类癌5例,神经内分泌癌52例,神经内分泌瘤17例；一期6例、二期21例、三期28例、四期19例。57例患者接受根治性手术治疗,12例患者接受姑息性手术治疗,5例患者行化疗。74例均获得随访,全组1、3、5年存活率分别为74.32%(55/74)、40.54%(30/74)、18.91%(14/74)。结论胃神经内分泌肿瘤好发于男性,发病年龄较迟,症状不典型,尽早接受根治性手术治疗能够有效的提高患者的生存率。
[Abstract]:Objective to study the pathogenesis, diagnosis, treatment and prognosis of 74 cases of gastric neuroendocrine tumors. Methods the clinical data and follow-up results of 74 patients with gastric neuroendocrine tumors treated in the first affiliated Hospital of Anhui Medical University from January 2008 to September 2013 were analyzed retrospectively. The data were processed by SPSS 16.0 software, and single factor survival analysis was carried out by Kaplan-Meier method. Results the average age of 74 patients with gastric neuroendocrine neoplasms was 62.86 years old, the ratio of male and female was 2.52: 1, 48 cases (64.86%) had first symptoms of abdominal discomfort, 21 cases (28.38%) had choking on food, reflux and warm air, black stool. There were 12 cases (16.21%) with wasting and other symptoms, including 5 cases of carcinoid, 52 cases of neuroendocrine carcinoma, 17 cases of neuroendocrine tumor, 6 cases of primary stage, 21 cases of secondary stage, 28 cases of stage 3. Twelve patients received palliative operation and 5 patients received palliative operation. All patients were followed up. The survival rates of the patients were 74.32% (55 / 74) and 40.54% (30 / 74), respectively. The survival rate of the patients was 18.91% (14 / 74), and the survival rates were 74.32% (55 / 74) and 40.54% (30 / 74), respectively. Conclusion gastric neuroendocrine neoplasms are more common in men with late onset age and atypical symptoms. Radical surgical treatment as early as possible can effectively improve the survival rate of patients.
【学位授予单位】：安徽医科大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R735.2
本文编号：2154300
[Abstract]:Objective to study the pathogenesis, diagnosis, treatment and prognosis of 74 cases of gastric neuroendocrine tumors. Methods the clinical data and follow-up results of 74 patients with gastric neuroendocrine tumors treated in the first affiliated Hospital of Anhui Medical University from January 2008 to September 2013 were analyzed retrospectively. The data were processed by SPSS 16.0 software, and single factor survival analysis was carried out by Kaplan-Meier method. Results the average age of 74 patients with gastric neuroendocrine neoplasms was 62.86 years old, the ratio of male and female was 2.52: 1, 48 cases (64.86%) had first symptoms of abdominal discomfort, 21 cases (28.38%) had choking on food, reflux and warm air, black stool. There were 12 cases (16.21%) with wasting and other symptoms, including 5 cases of carcinoid, 52 cases of neuroendocrine carcinoma, 17 cases of neuroendocrine tumor, 6 cases of primary stage, 21 cases of secondary stage, 28 cases of stage 3. Twelve patients received palliative operation and 5 patients received palliative operation. All patients were followed up. The survival rates of the patients were 74.32% (55 / 74) and 40.54% (30 / 74), respectively. The survival rate of the patients was 18.91% (14 / 74), and the survival rates were 74.32% (55 / 74) and 40.54% (30 / 74), respectively. Conclusion gastric neuroendocrine neoplasms are more common in men with late onset age and atypical symptoms. Radical surgical treatment as early as possible can effectively improve the survival rate of patients.
【学位授予单位】：安徽医科大学
【学位级别】：硕士
【学位授予年份】：2015
【分类号】：R735.2
【参考文献】
相关期刊论文 前1条
1 冯强;郑朝旭;冯晓莉;毕建军;;胃神经内分泌肿瘤临床病理特点及预后分析[J];中国普通外科杂志;2012年06期
，本文编号：2154300
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