射频消融与微波消融治疗肺肿瘤的对比研究

发布时间：2018-08-11 19:37

【摘要】：目的比较肺肿瘤射频消融与微波消融的近远期疗效及并发症,以期为临床选择消融手段提供依据。方法回顾性分析2007年3月至2014年12月间75例接受射频或者微波消融的肺肿瘤患者资料,比较近远期疗效及并发症。75例中射频消融43例,微波消融32例;男58例,女17例;原发性非小细胞肺癌51例,其他原发性肺肿瘤8例,转移性肺癌16例。两组患者治疗前的基线资料比较统计学处理无显著性差异(P0.05)。结果近期疗效方面射频消融有效率(CR+PR)为79.1%(34/43),微波消融有效率为68.8%(22/32),两组资料经统计学处理无显著性差异(χ~2=1.033,P=0.309);射频消融和微波消融的0.5、1、2、3、5年生存率分别为95.0%、77.3%、55.3%、42.0%、33.6%和92.0%、75.0%、43.8%、39.8%、26.6%,两组资料经统计学处理无显著性差异(χ~2=0.203,P=0.653)。37例出现并发症,其中射频消融与微波消融分别发生21例和16例,两组资料经统计学处理没有显著性差异。结论射频消融与微波消融在肺肿瘤治疗方面均是安全的,在近远期疗效和安全性方面均无显著性差异,临床上均可以选择。
[Abstract]:Objective to compare the effects and complications of radiofrequency ablation and microwave ablation on pulmonary tumors and to provide evidence for clinical selection of ablation methods. Methods from March 2007 to December 2014, 75 patients with pulmonary neoplasms underwent radiofrequency or microwave ablation were retrospectively analyzed. 43 patients (58 males, 17 females) underwent radiofrequency ablation (RFA), including 43 patients (58 males) and 17 females (17 females), of whom 43 received radiofrequency ablation (RFA) and 32 received microwave ablation. There were 51 cases of primary non-small cell lung cancer, 8 cases of other primary lung tumors and 16 cases of metastatic lung cancer. There was no significant difference in baseline data before treatment between the two groups (P0.05). Results the effective rate of radiofrequency ablation (CR PR) was 79.1% (34 / 43), and the effective rate of microwave ablation was 68.8% (22 / 32). There was no statistical difference between the two groups (蠂 ~ (21.033) P ~ (0.309). There was no significant difference between the two groups (蠂 2 / 0.203 P 0.653). There were 37 cases of complications. Radiofrequency ablation and microwave ablation occurred in 21 cases and 16 cases respectively. There was no significant difference between the two groups. Conclusion both radiofrequency ablation and microwave ablation are safe in the treatment of lung tumors, but there is no significant difference in the short-term and long-term efficacy and safety.
【作者单位】：广州市番禺区何贤纪念医院内四科(肿瘤内科);广东省医学科学院&广东省人民医院介入治疗科;
【基金】：广东省科技计划项目(编号:2010B080701089)
【分类号】：R734.2

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