肠内营养联合化疗治疗晚期胃癌的临床疗效研究

发布时间：2018-08-16 16:24

【摘要】：目的:探讨晚期胃癌化疗期间联合肠内营养治疗的价值。方法:本研究为前瞻性随机研究。按NRS 2002营养风险量表筛选具有营养不良风险的62例不可手术的晚期胃癌病人随机分为两组。两组病人均行奥沙利铂联合替吉奥化疗,对照组(n=30)在化疗的同时予营养咨询;治疗组(n=32)在化疗的同时予安素肠内营养治疗,所有病人在化疗前和化疗后行NRS 2002量表评估,观察并记录体重、体重指数、血清白蛋白,化疗结束后评价化疗疗效与不良反应。结果:化疗结束后肠内营养组血清白蛋白水平、体重及体重指数明显高于对照组(P0.05),两组病人化疗后不良反应和化疗疗效差别无统计学意义。结论:肠内营养联合化疗可改善晚期胃癌病人的营养状态,降低营养不良风险。
[Abstract]:Objective: to evaluate the value of combined enteral nutrition during chemotherapy for advanced gastric cancer. Methods: this study was a prospective randomized study. According to NRS 2002 nutritional risk scale, 62 patients with non-operative advanced gastric cancer with malnutrition risk were randomly divided into two groups. Two groups of patients were treated with oxaliplatin combined with tegugio chemotherapy, the control group (nf30) was treated with nutrition consultation while chemotherapy, the treatment group (nf32) was treated with enteral nutrition, and all patients were evaluated with NRS 2002 scale before and after chemotherapy. Body weight, body mass index, serum albumin, curative effect and adverse reaction were observed and recorded. Results: the levels of serum albumin, body weight and body mass index in enteral nutrition group after chemotherapy were significantly higher than those in control group (P0.05). Conclusion: enteral nutrition combined with chemotherapy can improve the nutritional status and reduce the risk of malnutrition in patients with advanced gastric cancer.
【作者单位】：厦门大学附属第一医院厦门市肿瘤医院肿瘤内科;
【分类号】：R459.3;R735.2

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