HPV阴性胃型子宫颈原位腺癌:一种具有胃和肠分化的罕见病变谱系
发布时间：2018-09-17 20:26
【摘要】：正作者报道9例罕见的具有胃和肠分化且与人类乳头瘤病毒(HPV)感染无关的子宫颈原位腺癌(AIS)。患者年龄25~73岁(平均51岁),所有病例均位于子宫颈鳞-柱交界区(或邻近),其中有3例延伸子宫下段,2例累及子宫内膜。所有病例均大部分保留正常子宫颈腺体结构,其中5例有轻度腺体复杂性增生。腺上皮从几乎为纯胃型(4例)至混合不同比例杯状细胞的胃肠型(5例)。与正常的子宫颈腺体嗜碱性细胞质不同,胃型上皮通常由明显嗜酸性或浅粉色胞
[Abstract]:The authors report 9 rare cases of cervical in situ adenocarcinoma (AIS). With gastric and intestinal differentiation unrelated to human papillomavirus (HPV) infection. The age of the patients was 2573 years (mean 51 years). All the patients were located at or near the squamous column junction of the cervix. Of them, 3 cases involved the endometrium in 2 cases with extension of the lower segment of the uterus. In all cases, the normal structure of cervical gland was preserved in most cases, of which 5 cases had mild hyperplasia of complex glands. The glandular epithelium changed from almost pure stomach type (4 cases) to gastrointestinal type mixed with different proportion of goblet cells (5 cases). Unlike the normal basophilic cytoplasm of the cervix glands, gastric epithelium is usually composed of distinct eosinophilic or light pink cells
【作者单位】： 解放军福州总医院病理科;福清市医院病理科;
【分类号】：R737.33
本文编号：2246998
[Abstract]:The authors report 9 rare cases of cervical in situ adenocarcinoma (AIS). With gastric and intestinal differentiation unrelated to human papillomavirus (HPV) infection. The age of the patients was 2573 years (mean 51 years). All the patients were located at or near the squamous column junction of the cervix. Of them, 3 cases involved the endometrium in 2 cases with extension of the lower segment of the uterus. In all cases, the normal structure of cervical gland was preserved in most cases, of which 5 cases had mild hyperplasia of complex glands. The glandular epithelium changed from almost pure stomach type (4 cases) to gastrointestinal type mixed with different proportion of goblet cells (5 cases). Unlike the normal basophilic cytoplasm of the cervix glands, gastric epithelium is usually composed of distinct eosinophilic or light pink cells
【作者单位】： 解放军福州总医院病理科;福清市医院病理科;
【分类号】：R737.33
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