淋巴细胞与单核细胞比值对原发性肝癌患者根治性切除术后预后的预测价值
发布时间：2018-09-19 16:40
【摘要】：目的:探讨外周血中淋巴细胞与单核细胞比值(LMR)对原发性肝癌(PLC)根治性切除术后预后的预测价值。方法:收集接受肝癌根治性切除术且术前未接受其他治疗的PLC患者447例的临床及实验室资料,根据术前外周血检查结果计算LMR,绘制术前LMR诊断患者术后5 a生存状态的ROC曲线,确定LMR诊断界值。采用Kaplan-Meier法和COX回归模型分析PLC患者术后5 a生存的影响因素。结果:术前LMR诊断界值为3.03,据此将LMR分为高(≥3.03)和低(3.03)两种状态。COX分析结果显示术前高LMR是PLC患者术后预后的保护因素(β=-0.329,HR=0.720,95%CI=0.562~0.921)。结论:术前LMR可用于评价PLC根治性切除术后患者的预后,术前高LMR患者预后较好。
[Abstract]:Objective: to investigate the prognostic value of lymphocyte to monocyte ratio (LMR) in peripheral blood in patients with primary liver cancer after (PLC) radical resection. Methods: the clinical and laboratory data of 447 PLC patients who underwent radical resection of liver cancer without other treatment were collected. According to the results of preoperative peripheral blood examination, LMR, was calculated to draw the ROC curve of the survival state of the patients diagnosed by LMR 5 years after operation. To determine the diagnostic limit of LMR. Kaplan-Meier method and COX regression model were used to analyze the factors influencing the survival of PLC patients 5 years after operation. Results: the diagnostic threshold of preoperative LMR was 3.03, according to which LMR was classified into high (鈮，
本文编号：2250716
[Abstract]:Objective: to investigate the prognostic value of lymphocyte to monocyte ratio (LMR) in peripheral blood in patients with primary liver cancer after (PLC) radical resection. Methods: the clinical and laboratory data of 447 PLC patients who underwent radical resection of liver cancer without other treatment were collected. According to the results of preoperative peripheral blood examination, LMR, was calculated to draw the ROC curve of the survival state of the patients diagnosed by LMR 5 years after operation. To determine the diagnostic limit of LMR. Kaplan-Meier method and COX regression model were used to analyze the factors influencing the survival of PLC patients 5 years after operation. Results: the diagnostic threshold of preoperative LMR was 3.03, according to which LMR was classified into high (鈮，
本文编号：2250716
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