柴胡疏肝散合桃红四物汤加减对肝癌TACE术后气滞血瘀型患者的临床观察
发布时间：2018-10-26 11:13
【摘要】：目的:本文主要通过观察柴胡疏肝散合桃红四物汤化裁方对肝癌TACE术后气滞血瘀型患者AFP及临床症状的影响,为原发性肝癌TACE术后气滞血瘀型患者的提供更多治疗方法。方法:将收集的60例原发性肝癌气滞血瘀型患者,按照随机数字表法,分成2组,每组30人,对照组给予肝癌TACE术及甘草酸二胺胶囊保肝治疗,治疗组在对照组的基础上口服柴胡疏肝散合桃红四物汤化裁方治疗。记录并分析两组患者用药前后AFP、KPS、中医症候的变化情况,观察并记录该方剂的临床疗效。结果:1.统计结果显示,两组患者AFP水平较治疗前均有所降低(p0.05),治疗后两组对比显示,治疗组比对照组AFP水平降低幅度较大(p0.05);2.统计结果显示,两组患者中医症候及KPS较治疗前均有所改善(p0.05),治疗后两组对比显示,治疗组比对照组中医症候及KPS改善较明显(p0.05);3.统计结果显示,两组患者在不良反应发生率上,治疗组与对照组比较无显著差异(p0.05)。结论:1.柴胡疏肝散合桃红四物汤化裁方联合肝癌TACE术能降低患者肿瘤标志物AFP的水平。2.柴胡疏肝散合桃红四物汤化裁方联合肝癌TACE术能够显著改善患者的中医症候,提高患者KPS评分。3.柴胡疏肝散合桃红四物汤化裁方对患者白细胞以及肝肾功能无不良影响。
[Abstract]:Objective: to observe the effect of Chaihu Shugan San and Taohong Siwu decoction on AFP and clinical symptoms of patients with qi stagnation and blood stasis after TACE operation of liver cancer, and to provide more treatment methods for patients with Qi stagnation and blood stasis after TACE. Methods: sixty patients with primary liver cancer with Qi stagnation and blood stasis were divided into 2 groups, 30 in each group. The control group was treated with hepatoma TACE and glycyrrhizin diamine capsule. The treatment group in the control group on the basis of oral Chaihu Shugan San Taohong Siwu decoction treatment. To record and analyze the changes of TCM symptoms of AFP,KPS, in both groups before and after medication, and to observe and record the clinical efficacy of the prescription. The result is 1: 1. The statistical results showed that the level of AFP in both groups was lower than that before treatment (p0.05). After treatment, the level of AFP in the treatment group was significantly lower than that in the control group (p0.05), and the level of AFP in the treatment group was significantly lower than that in the control group (p0.05). The statistical results showed that the symptoms of TCM and KPS were improved in both groups (p0.05). After treatment, the symptoms of TCM and KPS in the treatment group were significantly improved than those in the control group (p0.05). The results showed that there was no significant difference between the treatment group and the control group in the incidence of adverse reactions (p0.05). Conclusion: 1. Chaihu Shugan San and Taohong Siwu decoction combined with liver cancer TACE can reduce the level of tumor marker AFP. 2. Chaihu Shugan San combined with Taohong Siwu decoction combined with liver cancer TACE can significantly improve the TCM symptoms of patients and improve the KPS score of the patients. 3. Chaihu Shugan San and Taohong Siwu decoction had no adverse effect on white blood cells and liver and kidney function.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R735.7
本文编号：2295537
[Abstract]:Objective: to observe the effect of Chaihu Shugan San and Taohong Siwu decoction on AFP and clinical symptoms of patients with qi stagnation and blood stasis after TACE operation of liver cancer, and to provide more treatment methods for patients with Qi stagnation and blood stasis after TACE. Methods: sixty patients with primary liver cancer with Qi stagnation and blood stasis were divided into 2 groups, 30 in each group. The control group was treated with hepatoma TACE and glycyrrhizin diamine capsule. The treatment group in the control group on the basis of oral Chaihu Shugan San Taohong Siwu decoction treatment. To record and analyze the changes of TCM symptoms of AFP,KPS, in both groups before and after medication, and to observe and record the clinical efficacy of the prescription. The result is 1: 1. The statistical results showed that the level of AFP in both groups was lower than that before treatment (p0.05). After treatment, the level of AFP in the treatment group was significantly lower than that in the control group (p0.05), and the level of AFP in the treatment group was significantly lower than that in the control group (p0.05). The statistical results showed that the symptoms of TCM and KPS were improved in both groups (p0.05). After treatment, the symptoms of TCM and KPS in the treatment group were significantly improved than those in the control group (p0.05). The results showed that there was no significant difference between the treatment group and the control group in the incidence of adverse reactions (p0.05). Conclusion: 1. Chaihu Shugan San and Taohong Siwu decoction combined with liver cancer TACE can reduce the level of tumor marker AFP. 2. Chaihu Shugan San combined with Taohong Siwu decoction combined with liver cancer TACE can significantly improve the TCM symptoms of patients and improve the KPS score of the patients. 3. Chaihu Shugan San and Taohong Siwu decoction had no adverse effect on white blood cells and liver and kidney function.
【学位授予单位】：黑龙江中医药大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R735.7
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