ADC值在鉴别间变型与非间变型室管膜瘤中的应用

发布时间：2018-11-10 18:41

【摘要】：目的:探讨扩散加权成像和表观系数扩散(ADC)值在鉴别间变型管膜瘤与非间变型室管膜瘤中的价值。方法:回顾性分析我院经手术病理证实的52例室管膜瘤患者的病例资料,其中非间变型室管膜瘤27例,间变型室管膜瘤25例。测量肿瘤实质部分的最小、平均及最大ADC值,并采用ROC曲线分析其诊断效能。结果:间变型室管膜瘤的最小ADC值[(0.808±0.190)×10~(-3)mm~2/s]低于非间变型室管膜瘤[(1.093±0.365)×10~(-3)mm~2/s],差异有统计学意义(P0.05);鉴别两种肿瘤的最佳最小ADC值为0.887×10~(-3)mm~2/s,诊断敏感度为78.5%、特异度为73.2%。两种类型肿瘤的平均ADC值和最大ADC值的差异无统计学意义(P0.05)。结论:最小ADC值有助于间变型室管膜瘤与非间变型室管膜瘤的鉴别诊断。
[Abstract]:Objective: to evaluate the value of diffusion weighted imaging (DWI) and apparent coefficient diffusion (ADC) in differential diagnosis of intervariant and non-intervariant ependymoma. Methods: the data of 52 cases of ependymoma confirmed by operation and pathology in our hospital were retrospectively analyzed. Among them, 27 cases were non-anaplastic ependymoma and 25 cases were anaplastic ependymoma. The minimum, average and maximum ADC values of the tumor parenchyma were measured, and the diagnostic efficacy was analyzed by ROC curve. Results: the minimum ADC value of stromal ependymoma [(0.808 卤0.190) 脳 10 ~ (-3) mm~2/s] was significantly lower than that of non-intervariant ependymoma [(1.093 卤0.365) 脳 10 ~ (-3) mm~2/s] (P0.05). The best minimum ADC value for differentiating two kinds of tumors was 0.887 脳 10 ~ (-3) mm~2/s,. The diagnostic sensitivity was 78.5% and the specificity was 73.2%. There was no significant difference between the average ADC value and the maximum ADC value of the two types of tumors (P0.05). Conclusion: the minimum ADC value is helpful to the differential diagnosis of intermetamorphic ependymoma and non-anaplastic ependymoma.
【作者单位】：郑州大学第一附属医院磁共振室;
【基金】：河南省医学科技攻关计划项目(201602030)
【分类号】：R445.2;R739.4

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