直肠癌术后存活率围手术期影响因素分析与PNAG评分建立的研究
发布时间：2018-11-25 10:39
【摘要】：目的探讨临床病理学特征和围手术期全身炎症状况与直肠癌病人术后存活率的关系,建立炎症相关直肠癌存活率预测评分系统。方法回顾性分析中山大学附属第六医院2007年6月至2012年8月就诊的382例I~Ⅲ期直肠癌病人临床资料、围手术期炎症状况指标和术后随访情况。结果全组病人的中位随访时间为46个月,1、3、5年总存活率分别为96.7%、85.6%、77.4%,1、3、5年无病存活率为86.9%、72.0%、68.1%。多因素分析结果提示,年龄、病理TNM分期、大体分型、脉管浸润情况和PNAG评分是Ⅰ~Ⅲ期直肠癌术后总存活率的独立影响因素。病理TNM分期、脉管浸润情况、PNAG评分是Ⅰ~Ⅲ期直肠癌术后无病存活率的独立影响因素。结论直肠癌病人术后存活率受临床病理学特征危险因素和全身炎症状况的影响,PNAG评分作为一项反映围手术期全身炎症状况的综合指标,对于存活率预测具有重要意义。
[Abstract]:Objective to investigate the relationship between the clinicopathological features and perioperative systemic inflammation and postoperative survival rate of rectal cancer patients, and to establish a prognostic scoring system for the survival rate of patients with rectal cancer associated with inflammation. Methods the clinical data of 382 patients with stage I- 鈪，
本文编号：2355799
[Abstract]:Objective to investigate the relationship between the clinicopathological features and perioperative systemic inflammation and postoperative survival rate of rectal cancer patients, and to establish a prognostic scoring system for the survival rate of patients with rectal cancer associated with inflammation. Methods the clinical data of 382 patients with stage I- 鈪，
本文编号：2355799
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