胃癌D2根治术中纳米碳显影法应用研究

发布时间：2018-12-12 21:05

【摘要】：目的目前认为进展期胃癌分检35枚淋巴结更贴合患者准确病理分期,但常规分检淋巴结方法很难实现。本研究探讨纳米碳显影法在胃癌D2根治术中淋巴结分检中的应用优势。方法回顾性分析2015-10-01-2016-09-30河南省肿瘤医院普外科100例胃癌患者临床资料,按是否应用纳米碳显影分为纳米碳显影组(观察组)和非显影组(对照组),对照2组检出淋巴结总数、平均检出淋巴结数、淋巴结15枚例数、阳性淋巴结数、淋巴结阳性率、患者转移率、平均直径5mm数、平均直径5mm阳性淋巴结数、第1、2站淋巴结数和淋巴结分检时间等指标。结果观察组检出淋巴结总数(3 005枚)和阳性淋巴结总数(509枚)均高于对照组的1 560和305枚。观察组和对照组平均检出淋巴结数分别为62.943±14.507和32.436±5.743,差异有统计学意义,P0.001;淋巴结分检时间分别为(14.1±2.5)和(17.4±3.2)min,差异有统计学意义,P0.001;平均直径5mm数分别为28.972±7.819和9.503±3.390,差异有统计学意义,P0.001;平均直径5mm阳性淋巴结分别为17.065±7.610和11.124±8.376,差异有统计学意义,P=0.010;第1(36.605±12.720和19.391±4.518)和第2站淋巴结数(30.110±10.298和14.876±5.396)差异统计学意义,P0.001;淋巴结阳性率分别为(0.461±0.249)%和(0.453±0.272)%,差异无统计学意义,P=0.948。结论采用纳米碳显影方法在胃癌D2根治术的淋巴结分检中具有操作简便,获取淋巴结数目多,更有利于准确病理分期等优点。
[Abstract]:Objective it is considered that 35 lymph nodes of advanced gastric cancer are more suitable for accurate pathological staging, but routine lymph node detection is difficult to achieve. The purpose of this study was to investigate the advantages of nano-carbon imaging in the diagnosis of lymph nodes in D 2 radical gastrectomy of gastric cancer. Methods the clinical data of 100 patients with gastric cancer in general surgery department of Henan Cancer Hospital from January to September 30, 2015-01-2016-30 were retrospectively analyzed. The patients were divided into two groups according to whether they were treated with nano-carbon development (observation group) and non-developed group (control group). In the control group, the total number of lymph nodes detected, the average number of lymph nodes detected, the number of lymph nodes in 15 cases, the number of positive lymph nodes, the positive rate of lymph nodes, the metastatic rate of patients, the average diameter of 5mm, the number of 5mm positive lymph nodes of the average diameter, the number of positive lymph nodes in the The number of lymph nodes and the time of lymph node screening were measured at the 1st and 2nd station. Results the total number of lymph nodes (3 005) and positive lymph nodes (509) in the observation group were higher than those in the control group (1 560 and 305). The average number of detected lymph nodes in the observation group and the control group was 62.943 卤14.507 and 32.436 卤5.743 respectively, the difference was statistically significant (P 0.001). There were significant differences in lymph node detection time (14. 1 卤2. 5) and (17. 4 卤3. 2) min, respectively (P 0. 001), and the mean diameter 5mm numbers were 28.972 卤7.819 and 9.503 卤3. 390, respectively (P 0. 001). The mean diameter of 5mm positive lymph nodes was 17.065 卤7.610 and 11.124 卤8.376, respectively. The number of lymph nodes at the first (36.605 卤12.720) and the second (30.110 卤10.298) and the second (14.876 卤5.396) were significantly different (P 0.001). The positive rates of lymph nodes were (0.461 卤0.249)% and (0.453 卤0.272)%, respectively. Conclusion Nano-carbon imaging is a simple and convenient method to detect lymph nodes in D2 radical gastrectomy for gastric cancer. It is more convenient to obtain more lymph nodes and more beneficial to accurate pathological staging.
【作者单位】：河南省肿瘤医院普外科;
【基金】：河南省科技攻关项目(201403214)
【分类号】：R735.2

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