福建省仙游县335例胃癌环境危险因素的病例-对照研究

发布时间：2019-01-04 19:38

【摘要】：目的探讨胃癌的环境危险因素及其人群归因危险度。方法通过病例-对照研究,收集福建省仙游县医院经组织病理学确诊的新发胃癌共335例;同期按年龄、性别进行匹配,选取医院其他科室病人和健康人群作为对照。通过问卷调查获取病例及对照的饮食、饮食习惯等信息。应用条件Logistic回归进行胃癌环境危险因素的单因素和多因素分析并计算人群归因危险度。结果多因素条件Logistic回归分析结果:最早使用农药年龄≤18岁,饮食较烫,经常食用腌菜,经常辛辣饮食,高盐饮食为环境危险因素,人群归因危险度分别为38.95%、26.92%、25.38%、22.70%、21.59%,综合归因危险度为84.82%。结论使用农药、经常食用腌菜及不良饮食习惯(较烫、辛辣饮食及高盐饮食)是仙游县胃癌发生主要影响因素,指导仙游县居民正确喷洒农药、健康的饮食习惯对防控胃癌有重要意义。
[Abstract]:Objective to investigate the environmental risk factors and population attributable risk of gastric cancer. Methods 335 cases of newly diagnosed gastric cancer confirmed by histopathology in Xianyou County Hospital of Fujian Province were collected by case-control study and matched by age and sex. The information of diet and diet habits were obtained by questionnaire. Univariate and multivariate analysis of environmental risk factors of gastric cancer was performed by conditional Logistic regression and population attribution risk was calculated. Results the results of multivariate conditional Logistic regression analysis showed that the earliest age of pesticide use was less than 18 years old, the diet was hot, pickled vegetables, spicy diet, high salt diet were environmental risk factors, the attributable risk of population was 38.95, respectively. 26.92, 25.38, 22.70 and 21.59. the overall risk is 84.82. Conclusion Pesticide, regular consumption of pickled vegetables and bad eating habits (hot, spicy and high-salt diet) are the main influencing factors of gastric cancer in Xianyou County, and guide the residents of Xianyou County to spray pesticide correctly. Healthy eating habits are of great significance to the prevention and control of gastric cancer.
【作者单位】：福建卫生职业技术学院;福建医科大学公共卫生学院;福建省仙游县医院;
【基金】：福建省仙游县消化道肿瘤病因学、流行病学研究项目(2013B008) 福建省自然科学基金(2015J01673)
【分类号】：R735.2

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