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老年肺癌患者术后下肢深静脉血栓形成的危险因素

发布时间:2019-01-07 22:23
【摘要】:目的探讨肺癌术后发生下肢深静脉血栓(LEDVT)的主要危险因素。方法采用非随机同期对照研究方法,收集2013年3月至2015年12月在吉林大学第一医院胸外科收入院并施行手术治疗的肺癌患者108例,分为肺癌术后伴发LEDVT组36例和对照组72例,比较两组性别、年龄、体重指数(BMI)、是否患糖尿病、化疗情况、肿瘤分期、肿瘤病理类型以及手术方式、手术时间、术中出血情况等多种因素。结果两组术后是否合并2型糖尿病(T2DM)、术前是否行化疗、肺癌病理类型、肺癌分期、手术方式、手术时间等比较有统计学意义(P0.05)。Logistic二元回归分析提示肺癌病理类型、肺癌分期、手术方式等因素与肺癌术后LEDVT发生密切相关(OR=2.307、3.105、2.102)。结论肺腺癌、肺癌Ⅲ期、开胸手术是肺癌术后形成LEDVT的独立危险因素;肺癌患者在术前应评估发生LEDVT的风险,以期能早期预防、早期诊断,早期治疗,从而降低肺癌患者术后发生LEDVT的概率。
[Abstract]:Objective to investigate the main risk factors of (LEDVT) in lower extremity deep vein thrombosis after lung cancer operation. Methods from March 2013 to December 2015, 108 patients with lung cancer received surgical treatment in Department of Thoracic surgery, first Hospital of Jilin University, were divided into 36 patients with postoperative lung cancer associated with LEDVT and 72 patients in control group. The sex, age, body mass index (BMI),) of the two groups were compared for diabetes mellitus, chemotherapy, tumor staging, tumor pathological type, operation mode, operation time, intraoperative bleeding and so on. Results there were two groups: type 2 diabetes mellitus (T2DM), preoperative chemotherapy, pathological type of lung cancer, stage of lung cancer, operation mode. The time of operation was statistically significant (P0.05). Logistic binary regression analysis showed that lung cancer pathological type, lung cancer staging, surgical methods and other factors are closely related to the incidence of LEDVT (OR=2.307,3.105,2.102). Conclusion Lung adenocarcinoma, stage 鈪,

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