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骨盆软骨肉瘤临床特点和预后因素分析

发布时间:2019-01-08 10:00
【摘要】:目的·分析骨盆软骨肉瘤临床特点和预后因素,为临床诊治提供参考。方法·收集73例软骨肉瘤患者病例资料,其中24例为骨盆软骨肉瘤。总结骨盆软骨肉瘤的临床特点,分析其预后因素。结果·24例骨盆软骨肉瘤患者中,男女比1.4:1,中位年龄43.5岁。按Enneking骨盆肿瘤分区,Ⅰ区5例,Ⅱ区14例,Ⅲ区5例;组织学分级为软骨肉瘤I级的1例,Ⅱ级15例,Ⅲ级8例;组织学类型为普通中央型17例,去分化型3例,继发型2例,黏液型、间质型各1例。24例患者3、5和10年总生存率分别为(82.2±8.1)%、(77.3±8.9)%、(52.4±12.1)%。骨盆软骨肉瘤手术切除后局部复发率(83.3%)高于其他部位(34.7%),差异有统计学意义(P=0.000);最终接受截肢手术的比例(50.0%)也高于其他部位(20.4%),差异有统计学意义(P=0.000);但2组总生存时间比较,差异无统计学意义(P=0.216)。结论·骨盆软骨肉瘤局部复发率较高,更易导致截肢;术后较早复发,提示其预后不佳。
[Abstract]:Objective to analyze the clinical features and prognostic factors of pelvic chondrosarcoma. Methods 73 cases of chondrosarcoma were collected, including 24 cases of pelvic chondrosarcoma. To summarize the clinical features of pelvic chondrosarcoma and analyze its prognostic factors. Results in 24 patients with pelvic chondrosarcoma, the ratio of male to female was 1.4: 1, with a median age of 43.5 years. According to the division of pelvic tumor of Enneking, there were 5 cases in zone 鈪,

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