四君子汤联合肠内营养支持对胃癌术后生长激素、肿瘤标志物及免疫功能的影响

发布时间：2019-01-17 12:51

【摘要】：目的:研究四君子汤联合肠内营养支持对胃癌术后生长激素、肿瘤标志物及免疫功能的影响。方法:选择2015年2月至2016年4月在浙江中医药大学附属第一医院进行手术治疗的胃癌患者100例,将其分为2组,观察组在术后使用四君子汤联合肠内营养支持治疗,对照组则使用单一肠内营养支持,均治疗7天,观察术前及术后1、10天两组患者的生长激素水平、营养状态、肿瘤标志物以及免疫功能的变化。结果:两组患者治疗10天后的生长激素水平、肿瘤标志物(CEA、CA125、CA19-9)及免疫功能(Ig G、Ig A、CD4+、CD4+/CD8+)与术前比较均有显著改善(P0.05);且观察组上述指标改善显著优于对照组(P0.05)。结论:采用四君子汤联合肠内营养支持治疗胃癌手术后患者,能有效提高其生长激素水平,改善患者的营养状况及免疫功能,降低肿瘤标志物水平。
[Abstract]:Objective: to study the effects of Sijunzi decoction combined with enteral nutrition on growth hormone, tumor markers and immune function after gastric cancer surgery. Methods: from February 2015 to April 2016, 100 patients with gastric cancer underwent surgical treatment in the first affiliated Hospital of Zhejiang University of traditional Chinese Medicine were divided into two groups. The observation group was treated with Sijunzi decoction combined with enteral nutrition support after operation. The control group was treated with single enteral nutrition for 7 days. The levels of growth hormone, nutritional status, tumor markers and immune function were observed before and 10 days after operation. Results: the levels of growth hormone (GH), tumor marker (CEA,CA125,CA19-9) and immune function (Ig G Ag Ac CD4, CD4 / CD8) were significantly improved after 10 days of treatment in both groups (P0.05). The improvement of the above indexes in the observation group was significantly better than that in the control group (P0.05). Conclusion: Sijunzi decoction combined with enteral nutrition support can effectively improve the growth hormone level, improve the nutritional status and immune function of patients with gastric cancer, and decrease the level of tumor markers.
【作者单位】：浙江中医药大学第一临床医学院;
【分类号】：R735.2

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