食管癌术后早期肠内营养与肠外营养预防相关感染效果比较

发布时间：2019-01-20 11:52

【摘要】：目的比较食管癌术后早期肠内营养与肠外营养在预防感染中的效果,为医院感染的预防和控制工作提供客观依据。方法选取2013年1月-2017年6月于医院行食管癌切除术的100例患者为研究对象,分为试验组和对照组,每组各50例。术后,对照组患者给予全静脉肠外营养支持治疗,试验组患者给予早期肠内营养支持治疗。观察比较两组患者的术后感染率、术后排气时间和体质量下降水平。对两组患者术后1d、7d时的血清白蛋白(ALB)、血红蛋白(Hb)水平等营养指标及外周血淋巴细胞亚群指标进行检测和比较。结果试验组患者的术后总感染率为8.00%,低于对照组患者的24.00%(P0.05);治疗后,试验组患者的血清ALB、Hb水平及外周血CD_4~+、CD3+、CD_8~+、CD_4~+/CD_8~+优于对照组患者(P0.05);试验组患者的排气时间和体质量下降水平低于对照组患者(P0.05)。结论相对肠外营养支持治疗,在食管癌切除术后应用早期肠内营养支持治疗,能够降低患者术后感染率,改善患者的营养状态和细胞免疫功能指标,减少手术创伤,促进患者胃肠功能的恢复。
[Abstract]:Objective to compare the effect of early enteral nutrition and parenteral nutrition on the prevention of infection after esophageal cancer operation, and to provide objective basis for the prevention and control of nosocomial infection. Methods from January 2013 to June 2017, 100 patients with esophageal cancer were divided into experimental group and control group with 50 cases in each group. After operation, the patients in the control group were treated with total parenteral nutrition and the patients in the test group were treated with early enteral nutrition support. The postoperative infection rate, postoperative exhaust time and body mass were observed and compared between the two groups. The levels of serum albumin (ALB), hemoglobin (Hb) and peripheral blood lymphocyte subsets were measured and compared between the two groups on the 1st and 7th day after operation. Results the total infection rate of the patients in the trial group was 8.00%, which was lower than that in the control group (24.00%) (P0.05). After treatment, the levels of serum ALB,Hb and peripheral blood CD_4~, CD3, CD_8~, CD_4~ / CD_8~ in the experimental group were better than those in the control group (P0.05). The decrease of exhaust time and body mass in the trial group was lower than that in the control group (P0.05). Conclusion compared with parenteral nutrition support therapy, early enteral nutrition support therapy after resection of esophageal carcinoma can reduce postoperative infection rate, improve nutritional status and cellular immune function of patients, and reduce surgical trauma. To promote the recovery of gastrointestinal function in patients.
【作者单位】：衢州市人民医院心胸外科;
【基金】：浙江省中医药科学研究基金资助项目(2015ZA216)
【分类号】：R735.1

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