Radiomics方法研究应用进展
发布时间：2019-03-20 09:46
【摘要】：Radiomics(影像组学)方法是指对CT、MRI和PET等大量医学图像提取定量影像学特征并进行分析,找到疾病的影像学标识物,从而实现对疾病的精准预测、诊断及预后评估等。众所周知,癌症治疗是医学界面临的重要难题,尽早发现、尽早治疗能够极大地改善患者的生存率。肿瘤细胞的变化一般通过基因表达进行监测,但也可以通过影像学标识物进行监测,所以Radiomics方法被广泛应用于癌症的预测、早期诊断和治疗,是当今国内外影像医学及其相关专业的研究热点。本文首先对Radiomics方法中需要解决的4个关键性问题(包括多模态图像采集和重建、图像分割、特征提取和筛选、建立数据库对信息分析建模)分别进行详细的阐述;其次,介绍并分析Radiomics方法在早期预测及诊断非小细胞肺癌、前列腺癌、乳腺癌及其他癌症方面的应用;最后,预测Radiomics方法的未来发展趋势。
[Abstract]:Radiomics (Imaging histology) method refers to extracting quantitative imaging features of a large number of medical images, such as CT,MRI and PET, and finding out the imaging markers of the disease, so as to realize the accurate prediction, diagnosis and prognosis evaluation of the disease. As we all know, cancer treatment is an important problem facing the medical community. Early detection and early treatment can greatly improve the survival rate of patients. Changes in tumor cells are generally monitored by gene expression, but can also be monitored by imaging markers, so Radiomics is widely used in the prediction, early diagnosis and treatment of cancer. It is the research hotspot of imaging medicine and its related specialties at home and abroad. In this paper, the four key problems (including multi-modal image acquisition and reconstruction, image segmentation, feature extraction and selection, and the establishment of database for information analysis and modeling) in Radiomics method are described in detail. Secondly, the application of Radiomics method in early prediction and diagnosis of non-small cell lung cancer, prostate cancer, breast cancer and other cancers is introduced and analyzed. Finally, the future development trend of Radiomics method is predicted.
【作者单位】： 东北大学中荷生物医学与信息工程学院;
【基金】：国家自然科学基金资助项目(编号:61302013、61372014、81671773、61672146) 辽宁省工业攻关及成果产业化项目(编号:2014305001) 中央高校基本科研业务费项目(编号:N141008001)~~
【分类号】：R730.4
本文编号：2444095
[Abstract]:Radiomics (Imaging histology) method refers to extracting quantitative imaging features of a large number of medical images, such as CT,MRI and PET, and finding out the imaging markers of the disease, so as to realize the accurate prediction, diagnosis and prognosis evaluation of the disease. As we all know, cancer treatment is an important problem facing the medical community. Early detection and early treatment can greatly improve the survival rate of patients. Changes in tumor cells are generally monitored by gene expression, but can also be monitored by imaging markers, so Radiomics is widely used in the prediction, early diagnosis and treatment of cancer. It is the research hotspot of imaging medicine and its related specialties at home and abroad. In this paper, the four key problems (including multi-modal image acquisition and reconstruction, image segmentation, feature extraction and selection, and the establishment of database for information analysis and modeling) in Radiomics method are described in detail. Secondly, the application of Radiomics method in early prediction and diagnosis of non-small cell lung cancer, prostate cancer, breast cancer and other cancers is introduced and analyzed. Finally, the future development trend of Radiomics method is predicted.
【作者单位】： 东北大学中荷生物医学与信息工程学院;
【基金】：国家自然科学基金资助项目(编号:61302013、61372014、81671773、61672146) 辽宁省工业攻关及成果产业化项目(编号:2014305001) 中央高校基本科研业务费项目(编号:N141008001)~~
【分类号】：R730.4
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1 杨柳;临床CT图像中肝脏肿瘤分割研究[D];重庆大学;2013年
2 宗韵;慢性胃炎相关几种典型病灶的特征提取与识别[D];浙江大学;2016年
3 逄敏;乳腺X线图像肿块特征提取与特征变换方法研究[D];西安电子科技大学;2015年
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