前哨淋巴结微转移的临床意义
发布时间：2019-03-28 10:28
【摘要】：前哨淋巴结(Sentinel lymph node,SLN)的状态是影响乳腺癌患者预后的重要因素之一,同时它在局部腋窝治疗方式上也具有指导意义?但随着新技术(快速免疫组化,流式细胞术,RT-PCR等)在淋巴结活检中的应用,越来越多的SLN微小转移被发现,且它的临床意义尚存争议,这为它目前的治疗方式带来了诸多疑惑。尽管当前较多的研究推荐对前哨淋巴结微转移患者应用前哨淋巴结活检术替代腋窝清扫术,但该建议缺乏可靠的证据支撑,其可行性仍需进一步研究。作者通过阅读近年来国内外相关文献,就乳腺癌前哨淋巴结微转移的临床意义作一综述。
[Abstract]:The state of sentinel lymph node (Sentinel lymph node,SLN) is one of the important factors affecting the prognosis of patients with breast cancer. But with the application of new techniques (rapid immunohistochemistry, flow cytometry, RT-PCR, etc.) in lymph node biopsies, more and more micrometastases of SLN have been discovered, and its clinical significance remains controversial. This raises a lot of doubts about the way it is currently treated. Although Sentinel lymph node biopsy is recommended to replace axillary dissection in patients with Sentinel lymph node micrometastasis, there is no reliable evidence to support it, and its feasibility needs to be further studied. The authors reviewed the clinical significance of sentinel lymph node micrometastasis in breast cancer by reading related literatures at home and abroad in recent years.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R737.9
本文编号：2448779
[Abstract]:The state of sentinel lymph node (Sentinel lymph node,SLN) is one of the important factors affecting the prognosis of patients with breast cancer. But with the application of new techniques (rapid immunohistochemistry, flow cytometry, RT-PCR, etc.) in lymph node biopsies, more and more micrometastases of SLN have been discovered, and its clinical significance remains controversial. This raises a lot of doubts about the way it is currently treated. Although Sentinel lymph node biopsy is recommended to replace axillary dissection in patients with Sentinel lymph node micrometastasis, there is no reliable evidence to support it, and its feasibility needs to be further studied. The authors reviewed the clinical significance of sentinel lymph node micrometastasis in breast cancer by reading related literatures at home and abroad in recent years.
【学位授予单位】：重庆医科大学
【学位级别】：硕士
【学位授予年份】：2017
【分类号】：R737.9
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